The Resource Animal models of acute neurological injury, Jun Chen, Zao C. Xu, Xiao Ming Xu, John H. Zhang, editors
Animal models of acute neurological injury, Jun Chen, Zao C. Xu, Xiao Ming Xu, John H. Zhang, editors
Resource Information
The item Animal models of acute neurological injury, Jun Chen, Zao C. Xu, Xiao Ming Xu, John H. Zhang, editors represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Liverpool.This item is available to borrow from 1 library branch.
Resource Information
The item Animal models of acute neurological injury, Jun Chen, Zao C. Xu, Xiao Ming Xu, John H. Zhang, editors represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Liverpool.
This item is available to borrow from 1 library branch.
- Summary
- Despite numerous recent studies and exciting discoveries in the field, only limited treatments are available today for the victims of acute brain and spinal cord injuries. Animal Models of Acute Neurological Injuries, Second Edition, provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that often inhibit advances in this specialized research field. In the 10 years since publication of the first edition of this book, some animal models have become obsolete, some have stood the test of time, and newer models have emerged to enhance our knowledge of acute neurological injuries. The second edition continues to offer the research community tested approaches for this area of investigation. As with the first edition, top experts have developed and contributed these animal models. The books focus remains hands-on, practical applications of the models, rather than a theoretical approach. Each chapter contains a proven procedure enhanced by clear figures, illustrations, or videos. This new edition presents its readily reproducible protocols with clarity and consistency to best aid neuroscientists and neurobiologists. As with the first edition, the second edition is comprehensive and cutting-edge. Animal Models of Acute Neurological Injuries, Second Edition, is an ideal guide for research professionals, at all stages of their careers, who wish to pursue this vital course of study with the proficiency and precision required by the field
- Language
- eng
- Edition
- Second edition.
- Extent
- 1 online resource
- Note
- Includes index
- Contents
-
- Intro; Preface; Contents; Part I: Animal Care and Surgery; Animal Protocol; Regulatory Oversight; Designing the Animal Protocol; Writing the Animal Protocol; References; Anesthesia and Analgesia for Research Animals; Introduction; Pre-anesthetic Considerations and Monitoring; Injectable Anesthetics; Bartiturates; Ketamine; Propofol; Sedative/Tranquilizers; Local Anesthetics; Gaseous Agents; Isoflurane; Sevoflurane; Other Inhalants; Hypothermia; Analgesia; Opioids; Non-steroidal Anti-inflammatory Drugs (NSAIDs); Other Analgesics
- Special Considerations-Anesthesia and Analgesia for Animal Models of Neurologic DiseasesCerebral Ischemia and Hemorrhage Models; Physiologic Effects of Anesthesia and the Impact on Cerebral Ischemia and Hemorrhage Models; Anesthetic Considerations; Analgesic Considerations; Traumatic Brain Injury Models; Anesthetic Considerations; Analgesic Considerations; Spinal Cord Injury Models; Physiologic Effects of Anesthesia and the Impact on SCI Models; Anesthetic and Analgesic Agents Impact Spinal Injury Models; References; Rodent Surgical Procedures and Tissue Collection; Introduction
- Airway Management in the Rodent ModelIntubation; Materials; Procedures; Transcardiac Perfusion and Fixation; Equipment and Materials; Step by Step Procedures; Methods of Brain Removal; Materials; Procedures; Brain Removal; Separation of the Brain into Anatomical Sections; Materials; Procedure; Preparation of Brain Slices for Triphenyltetrazolium Chloride Staining; Materials; Procedure; References; Brain Monitoring; Introduction; Model Selection; Materials; Intravenous Femoral Catheter; Procedure; Burr Hole and Brain Monitoring; Postoperative Care; Conclusion; References
- Veterinary Care Methods for Rats and Mice in Experimental Spinal Cord Injury Studies: An UpdateModel Selection; Materials and Methods; Before Surgery and SCI; Surgery and SCI; Sterilization; Preparation; Surgery and SCI; Acutely and the First Week After Surgery and SCI; Housing; Veterinary Care; Chronically After Surgery and SCI; References; Part II: Cerebral Ischemic Animal Models; Four-Vessel Occlusion Model in Rats; Model Selection; Materials; Animal; Anesthesia; Equipment; Anesthesia; Surgery; Recording of Ischemic Depolarization; Procedures; Original 4-VO Model
- Placement of Occluding Device Around Carotid ArteryElectrocauterization of Vertebral Artery; Occlusion of Bilateral Common Carotid Arteries; One-Day 4-VO Model (with ID Recording); Surgical Preparation; ID Recording; Outcome Evaluation; Ischemic Cell Death in the Hippocampus; Ischemic Cell Death in the Striatum; Advantages, Complications and Limitations; Advantages; Complications; Limitations; Technical Difficulties; Mortality; Variation; References; Rat Model of Global Cerebral Ischemia: The Two-Vessel Occlusion (2VO) Model of Forebrain Ischemia; Introduction
- Isbn
- 9783030160821
- Label
- Animal models of acute neurological injury
- Title
- Animal models of acute neurological injury
- Statement of responsibility
- Jun Chen, Zao C. Xu, Xiao Ming Xu, John H. Zhang, editors
- Language
- eng
- Summary
- Despite numerous recent studies and exciting discoveries in the field, only limited treatments are available today for the victims of acute brain and spinal cord injuries. Animal Models of Acute Neurological Injuries, Second Edition, provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that often inhibit advances in this specialized research field. In the 10 years since publication of the first edition of this book, some animal models have become obsolete, some have stood the test of time, and newer models have emerged to enhance our knowledge of acute neurological injuries. The second edition continues to offer the research community tested approaches for this area of investigation. As with the first edition, top experts have developed and contributed these animal models. The books focus remains hands-on, practical applications of the models, rather than a theoretical approach. Each chapter contains a proven procedure enhanced by clear figures, illustrations, or videos. This new edition presents its readily reproducible protocols with clarity and consistency to best aid neuroscientists and neurobiologists. As with the first edition, the second edition is comprehensive and cutting-edge. Animal Models of Acute Neurological Injuries, Second Edition, is an ideal guide for research professionals, at all stages of their careers, who wish to pursue this vital course of study with the proficiency and precision required by the field
- Cataloging source
- EBLCP
- Dewey number
- 612.8
- Index
- index present
- LC call number
- RC337
- LC item number
- .A55 2019
- Literary form
- non fiction
- Nature of contents
- dictionaries
- http://library.link/vocab/relatedWorkOrContributorName
-
- Chen, Jun
- Xu, Zao C.
- Xu, Xiao-Ming
- Zhang, J. H.
- Series statement
- Springer series in translational stroke research
- http://library.link/vocab/subjectName
-
- Nervous system
- Nervous system
- Nervous system
- Label
- Animal models of acute neurological injury, Jun Chen, Zao C. Xu, Xiao Ming Xu, John H. Zhang, editors
- Note
- Includes index
- Antecedent source
- unknown
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
-
- Intro; Preface; Contents; Part I: Animal Care and Surgery; Animal Protocol; Regulatory Oversight; Designing the Animal Protocol; Writing the Animal Protocol; References; Anesthesia and Analgesia for Research Animals; Introduction; Pre-anesthetic Considerations and Monitoring; Injectable Anesthetics; Bartiturates; Ketamine; Propofol; Sedative/Tranquilizers; Local Anesthetics; Gaseous Agents; Isoflurane; Sevoflurane; Other Inhalants; Hypothermia; Analgesia; Opioids; Non-steroidal Anti-inflammatory Drugs (NSAIDs); Other Analgesics
- Special Considerations-Anesthesia and Analgesia for Animal Models of Neurologic DiseasesCerebral Ischemia and Hemorrhage Models; Physiologic Effects of Anesthesia and the Impact on Cerebral Ischemia and Hemorrhage Models; Anesthetic Considerations; Analgesic Considerations; Traumatic Brain Injury Models; Anesthetic Considerations; Analgesic Considerations; Spinal Cord Injury Models; Physiologic Effects of Anesthesia and the Impact on SCI Models; Anesthetic and Analgesic Agents Impact Spinal Injury Models; References; Rodent Surgical Procedures and Tissue Collection; Introduction
- Airway Management in the Rodent ModelIntubation; Materials; Procedures; Transcardiac Perfusion and Fixation; Equipment and Materials; Step by Step Procedures; Methods of Brain Removal; Materials; Procedures; Brain Removal; Separation of the Brain into Anatomical Sections; Materials; Procedure; Preparation of Brain Slices for Triphenyltetrazolium Chloride Staining; Materials; Procedure; References; Brain Monitoring; Introduction; Model Selection; Materials; Intravenous Femoral Catheter; Procedure; Burr Hole and Brain Monitoring; Postoperative Care; Conclusion; References
- Veterinary Care Methods for Rats and Mice in Experimental Spinal Cord Injury Studies: An UpdateModel Selection; Materials and Methods; Before Surgery and SCI; Surgery and SCI; Sterilization; Preparation; Surgery and SCI; Acutely and the First Week After Surgery and SCI; Housing; Veterinary Care; Chronically After Surgery and SCI; References; Part II: Cerebral Ischemic Animal Models; Four-Vessel Occlusion Model in Rats; Model Selection; Materials; Animal; Anesthesia; Equipment; Anesthesia; Surgery; Recording of Ischemic Depolarization; Procedures; Original 4-VO Model
- Placement of Occluding Device Around Carotid ArteryElectrocauterization of Vertebral Artery; Occlusion of Bilateral Common Carotid Arteries; One-Day 4-VO Model (with ID Recording); Surgical Preparation; ID Recording; Outcome Evaluation; Ischemic Cell Death in the Hippocampus; Ischemic Cell Death in the Striatum; Advantages, Complications and Limitations; Advantages; Complications; Limitations; Technical Difficulties; Mortality; Variation; References; Rat Model of Global Cerebral Ischemia: The Two-Vessel Occlusion (2VO) Model of Forebrain Ischemia; Introduction
- Control code
- on1110486583
- Dimensions
- unknown
- Edition
- Second edition.
- Extent
- 1 online resource
- File format
- unknown
- Form of item
- online
- Isbn
- 9783030160821
- Level of compression
- unknown
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
-
- 10.1007/978-3-030-16
- 10.1007/978-3-030-16082-1
- Quality assurance targets
- not applicable
- Reformatting quality
- unknown
- Sound
- unknown sound
- Specific material designation
- remote
- System control number
- (OCoLC)1110486583
- Label
- Animal models of acute neurological injury, Jun Chen, Zao C. Xu, Xiao Ming Xu, John H. Zhang, editors
- Note
- Includes index
- Antecedent source
- unknown
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
-
- Intro; Preface; Contents; Part I: Animal Care and Surgery; Animal Protocol; Regulatory Oversight; Designing the Animal Protocol; Writing the Animal Protocol; References; Anesthesia and Analgesia for Research Animals; Introduction; Pre-anesthetic Considerations and Monitoring; Injectable Anesthetics; Bartiturates; Ketamine; Propofol; Sedative/Tranquilizers; Local Anesthetics; Gaseous Agents; Isoflurane; Sevoflurane; Other Inhalants; Hypothermia; Analgesia; Opioids; Non-steroidal Anti-inflammatory Drugs (NSAIDs); Other Analgesics
- Special Considerations-Anesthesia and Analgesia for Animal Models of Neurologic DiseasesCerebral Ischemia and Hemorrhage Models; Physiologic Effects of Anesthesia and the Impact on Cerebral Ischemia and Hemorrhage Models; Anesthetic Considerations; Analgesic Considerations; Traumatic Brain Injury Models; Anesthetic Considerations; Analgesic Considerations; Spinal Cord Injury Models; Physiologic Effects of Anesthesia and the Impact on SCI Models; Anesthetic and Analgesic Agents Impact Spinal Injury Models; References; Rodent Surgical Procedures and Tissue Collection; Introduction
- Airway Management in the Rodent ModelIntubation; Materials; Procedures; Transcardiac Perfusion and Fixation; Equipment and Materials; Step by Step Procedures; Methods of Brain Removal; Materials; Procedures; Brain Removal; Separation of the Brain into Anatomical Sections; Materials; Procedure; Preparation of Brain Slices for Triphenyltetrazolium Chloride Staining; Materials; Procedure; References; Brain Monitoring; Introduction; Model Selection; Materials; Intravenous Femoral Catheter; Procedure; Burr Hole and Brain Monitoring; Postoperative Care; Conclusion; References
- Veterinary Care Methods for Rats and Mice in Experimental Spinal Cord Injury Studies: An UpdateModel Selection; Materials and Methods; Before Surgery and SCI; Surgery and SCI; Sterilization; Preparation; Surgery and SCI; Acutely and the First Week After Surgery and SCI; Housing; Veterinary Care; Chronically After Surgery and SCI; References; Part II: Cerebral Ischemic Animal Models; Four-Vessel Occlusion Model in Rats; Model Selection; Materials; Animal; Anesthesia; Equipment; Anesthesia; Surgery; Recording of Ischemic Depolarization; Procedures; Original 4-VO Model
- Placement of Occluding Device Around Carotid ArteryElectrocauterization of Vertebral Artery; Occlusion of Bilateral Common Carotid Arteries; One-Day 4-VO Model (with ID Recording); Surgical Preparation; ID Recording; Outcome Evaluation; Ischemic Cell Death in the Hippocampus; Ischemic Cell Death in the Striatum; Advantages, Complications and Limitations; Advantages; Complications; Limitations; Technical Difficulties; Mortality; Variation; References; Rat Model of Global Cerebral Ischemia: The Two-Vessel Occlusion (2VO) Model of Forebrain Ischemia; Introduction
- Control code
- on1110486583
- Dimensions
- unknown
- Edition
- Second edition.
- Extent
- 1 online resource
- File format
- unknown
- Form of item
- online
- Isbn
- 9783030160821
- Level of compression
- unknown
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
-
- 10.1007/978-3-030-16
- 10.1007/978-3-030-16082-1
- Quality assurance targets
- not applicable
- Reformatting quality
- unknown
- Sound
- unknown sound
- Specific material designation
- remote
- System control number
- (OCoLC)1110486583
Subject
- Nervous system -- Diseases | Animal models -- Handbooks, manuals, etc
- Nervous system -- Pathophysiology | Animal models -- Handbooks, manuals, etc
- Nervous system -- Wounds and injuries -- Handbooks, manuals, etc
Genre
Member of
- Online access with purchase: Springer
- Springer series in translational stroke research
- Springer series in translational stroke research.
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