Coverart for item
The Resource Arthritis research : methods and protocols, Volume 1, edited by Andrew P. Cope, (electronic book)

Arthritis research : methods and protocols, Volume 1, edited by Andrew P. Cope, (electronic book)

Label
Arthritis research : methods and protocols, Volume 1
Title
Arthritis research
Title remainder
methods and protocols
Title number
Volume 1
Statement of responsibility
edited by Andrew P. Cope
Contributor
Editor
Subject
Genre
Language
eng
Summary
Arthritis Research: Methods and Protocols is a compendium of data pertinent to the methods and protocols that have contributed to recent advances in molecular medicine in general, but to the molecular basis of rheumatic disease in particular. These volumes details novel technologies, some of which are still evolving and whose impacts are yet to be determined. Leaders in the field contribute to cover such exciting and cutting edge topics as imaging and immunohistochemistry, analysis of cartilage and bone catabolism, immunobiology, and cell trafficking. In Volume 1, authors discuss synovial joint morphology, histopathology, and immunohistochemistry, cartilage matrix and bone biology, and cell trafficking, migration and invasion. Volume 2 is broken up into sections that cover immunobiology and T cells, animal models of arthritis, and applications of new technologies, such as Differential Display Reverse Transcription-Polymerase Chain Reaction (DDRT-PCR), to define novel therapeutic targets. Both volumes combine to produce a concise set of protocols condensing decades of experience and expertise. Arthritis Research: Methods and Protocols will be a valuable tool for basic research investigators, clinician scientists, pathologists, immunologists, and biochemists looking to stay current in their fields
Member of
Cataloging source
N$T
Dewey number
616.7/220072
Illustrations
  • illustrations
  • plates
Index
index present
LC call number
RC933
LC item number
.A665245eb vol. 1
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
Cope, Andrew P.
http://library.link/vocab/subjectName
  • Arthritis
  • Arthritis
  • Arthritis
  • Laboratory Techniques and Procedures
Label
Arthritis research : methods and protocols, Volume 1, edited by Andrew P. Cope, (electronic book)
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
I. Synovial Joint Morphology, Histopathology, and Immunohistochemistry -- 1. Imaging Inflamed Synovial Joints -- 2. Arthroscopy as a Research Tool: A Review -- 3. Immunohitochemistry of the Inflamed Synovium -- 4. In Situ Hybridisation of Synovial Tissue -- 5. Subtractive Hybridization -- 6. Laser Capture as a Tool for Analysis of Gene Expression in Inflamed Synovium -- 7. Preparation of Mononuclear Cells from Synovial Tissue -- 8. Quantitative Image Analysis of Synovial Tissue -- II. Cartilage Matrix and Bone Biology -- 9. Cartilage Histomorphometry -- 10. Image Analysis of Aggrecan Degradation in Articular Cartilage with Formalin-Fixed Samples -- 11. In Situ Detection of Cell Death in Articular Cartilage -- 12. Measurement of Glycosaminoglycan Release from Cartilage Explants -- 13. Assessment of Collagenase Activity in Cartilage -- 14. Assessment of Gelatinase Expression and Activity in Articular Cartilage -- 15. Analysis of MT1-MMP Activity -- 16. Analysis of TIMP Expression and Activity -- 17. Bone Histomorphology in Arthritis Models -- 18. Generation of Osteoclasts in vitro and Assay of Osteoclast Activity -- III. Cell Trafficking, Migration and Invasion -- 19. Isolation and Analysis of Large and Small Vessel Endothelial Cells -- 20. Analysis of Flow Based Adhesion in vitro -- 21. Analysis of Leukocyte Recruitment in Synovial Microcirculation by Intravital Microscopy -- 22. Angiogenesis in Arthritis -- Methodological and Analytical Details -- 23. Analysis of Inflammatory Leukocyte and Endothelial Chemotactic Activity -- 24. Acquisition, Culture and Phenotyping of Synovial Fibroblasts -- 25. Genotyping of Synovial Fibroblasts: cDNA Array in Combination with RAP-PCR in Arthritis -- 26. Gene Transfer to Synovial Fibroblast -- Methods and Evaluation in the SCID Mouse Model -- 27. In vitro Matrigel Fibroblast Invasion Assay -- 28. Culture and Analysis of Circulating Fibrocytes
Control code
SPR226300496
Dimensions
unknown
Extent
1 online resource (1 volume)
File format
unknown
Form of item
online
Isbn
9781597454018
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color).
Quality assurance targets
not applicable
Reformatting quality
unknown
Reproduction note
Electronic resource.
Sound
unknown sound
Specific material designation
remote
Label
Arthritis research : methods and protocols, Volume 1, edited by Andrew P. Cope, (electronic book)
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
I. Synovial Joint Morphology, Histopathology, and Immunohistochemistry -- 1. Imaging Inflamed Synovial Joints -- 2. Arthroscopy as a Research Tool: A Review -- 3. Immunohitochemistry of the Inflamed Synovium -- 4. In Situ Hybridisation of Synovial Tissue -- 5. Subtractive Hybridization -- 6. Laser Capture as a Tool for Analysis of Gene Expression in Inflamed Synovium -- 7. Preparation of Mononuclear Cells from Synovial Tissue -- 8. Quantitative Image Analysis of Synovial Tissue -- II. Cartilage Matrix and Bone Biology -- 9. Cartilage Histomorphometry -- 10. Image Analysis of Aggrecan Degradation in Articular Cartilage with Formalin-Fixed Samples -- 11. In Situ Detection of Cell Death in Articular Cartilage -- 12. Measurement of Glycosaminoglycan Release from Cartilage Explants -- 13. Assessment of Collagenase Activity in Cartilage -- 14. Assessment of Gelatinase Expression and Activity in Articular Cartilage -- 15. Analysis of MT1-MMP Activity -- 16. Analysis of TIMP Expression and Activity -- 17. Bone Histomorphology in Arthritis Models -- 18. Generation of Osteoclasts in vitro and Assay of Osteoclast Activity -- III. Cell Trafficking, Migration and Invasion -- 19. Isolation and Analysis of Large and Small Vessel Endothelial Cells -- 20. Analysis of Flow Based Adhesion in vitro -- 21. Analysis of Leukocyte Recruitment in Synovial Microcirculation by Intravital Microscopy -- 22. Angiogenesis in Arthritis -- Methodological and Analytical Details -- 23. Analysis of Inflammatory Leukocyte and Endothelial Chemotactic Activity -- 24. Acquisition, Culture and Phenotyping of Synovial Fibroblasts -- 25. Genotyping of Synovial Fibroblasts: cDNA Array in Combination with RAP-PCR in Arthritis -- 26. Gene Transfer to Synovial Fibroblast -- Methods and Evaluation in the SCID Mouse Model -- 27. In vitro Matrigel Fibroblast Invasion Assay -- 28. Culture and Analysis of Circulating Fibrocytes
Control code
SPR226300496
Dimensions
unknown
Extent
1 online resource (1 volume)
File format
unknown
Form of item
online
Isbn
9781597454018
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color).
Quality assurance targets
not applicable
Reformatting quality
unknown
Reproduction note
Electronic resource.
Sound
unknown sound
Specific material designation
remote

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