Coverart for item
The Resource Asthma : targeted biological therapies, Girolamo Pelaia, Alessandro Vatrella, Rosario Maselli

Asthma : targeted biological therapies, Girolamo Pelaia, Alessandro Vatrella, Rosario Maselli

Label
Asthma : targeted biological therapies
Title
Asthma
Title remainder
targeted biological therapies
Statement of responsibility
Girolamo Pelaia, Alessandro Vatrella, Rosario Maselli
Creator
Contributor
Author
Subject
Language
eng
Summary
This book focuses on the fundamentals of the use of biologics in asthma, describing the rationale, principles, mechanisms of action, and indications. It offers an excellent balance between basic science and the analysis of clinical trials, updating readers with new developments that are changing the global scenario for targeted biological anti-asthma therapies, especially with regard to more severe disease. A range of therapies are considered, from the humanized monoclonal anti-IgE antibody omalizumab, widely approved as add-on treatment for inadequately controlled disease, through to emerging biologics for which evidence supportive of efficacy is accumulating, including anti-IL-5, anti-IL-4, and anti-IL-13 therapies. One aspect to emerge is the variability in individual response, which suggests a need for characterization of different asthma subtypes to permit the effective implementation of phenotype-targeted treatments. This book will be of interest for pulmonologists, clinical immunologists, and physicians seeking sound information on these therapies, but also for scientists and pharmacologists wishing to enhance their knowledge of the therapeutic implications of the cellular and molecular mechanisms that underlie severe, uncontrolled asthma
Member of
Cataloging source
N$T
http://library.link/vocab/creatorName
Pelaia, Girolamo
Dewey number
616.2/3806
Index
no index present
LC call number
RC591
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Vatrella, Alessandro
  • Maselli, Rosario
http://library.link/vocab/subjectName
  • Asthma
  • Medicine & Public Health
  • Pneumology/Respiratory System
  • Allergology
  • Pharmacology/Toxicology
  • General Practice / Family Medicine
  • Pediatrics
Label
Asthma : targeted biological therapies, Girolamo Pelaia, Alessandro Vatrella, Rosario Maselli
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction -- Inflammatory cellular patterns in asthma -- Airway remodelling in asthma -- Anti-IgE antibodies -- IL-5-targeted antibodies -- IL-4-specific biologics -- Anti-IL-13 therapies -- Anti-TNFalpha-antibodies -- Biologic treatments targeted to innate cytokines -- Other biologic drugs -- Conclusions and future perspectives
Dimensions
unknown
Extent
1 online resource
File format
unknown
Form of item
online
Isbn
9783319460079
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-3-319-46007-9
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
ocn962750908
Label
Asthma : targeted biological therapies, Girolamo Pelaia, Alessandro Vatrella, Rosario Maselli
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction -- Inflammatory cellular patterns in asthma -- Airway remodelling in asthma -- Anti-IgE antibodies -- IL-5-targeted antibodies -- IL-4-specific biologics -- Anti-IL-13 therapies -- Anti-TNFalpha-antibodies -- Biologic treatments targeted to innate cytokines -- Other biologic drugs -- Conclusions and future perspectives
Dimensions
unknown
Extent
1 online resource
File format
unknown
Form of item
online
Isbn
9783319460079
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-3-319-46007-9
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
ocn962750908

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