Coverart for item
The Resource Capillary fluid exchange : regulation, functions, and pathology, Joshua Scallan, Virgina H. Huxley, and Ronald J. Korthuis, (electronic book)

Capillary fluid exchange : regulation, functions, and pathology, Joshua Scallan, Virgina H. Huxley, and Ronald J. Korthuis, (electronic book)

Label
Capillary fluid exchange : regulation, functions, and pathology
Title
Capillary fluid exchange
Title remainder
regulation, functions, and pathology
Statement of responsibility
Joshua Scallan, Virgina H. Huxley, and Ronald J. Korthuis
Title variation
Synthesis lectures on integrated systems physiology, from molecules to function
Creator
Contributor
Subject
Language
eng
Summary
The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the extracellular matrix and lymphatics. In addition to its role in the regulation of vascular volume, transcapillary fluid filtration also allows for continuous turnover of water bathing tissue cells, providing the medium for diffusional flux of oxygen and nutrients required for cellular metabolism and removal of metabolic byproducts. Transendothelial volume flow has also been shown to influence vascular smooth muscle tone in arterioles, hydraulic conductivity in capillaries, and neutrophil transmigration across postcapillary venules, while the flow of this filtrate through the interstitial spaces functions to modify the activities of parenchymal, resident tissue, and metastasizing tumor cells. Likewise, the flow of lymph, which is driven by capillary filtration, is important for the transport of immune and tumor cells, antigen delivery to lymph nodes, and for return of filtered fluid and extravasated proteins to the blood. Given this background, the aims of this treatise are to summarize our current understanding of the factors involved in the regulation of transcapillary fluid movement, how fluid movements across the endothelial barrier and through the interstitium and lymphatic vessels influence cell function and behavior, and the pathophysiology of edema formation
Member of
Cataloging source
CaBNvSL
http://library.link/vocab/creatorName
Scallan, Joshua
Dewey number
612.13
Illustrations
illustrations
Index
no index present
LC call number
QP106.6
LC item number
.S323 2010
Literary form
non fiction
Nature of contents
  • dictionaries
  • abstracts summaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Huxley, Virginia Heathorn.
  • Korthuis, Ronald J
Series statement
Colloquium lectures on integrated systems physiology, from molecules to function
Series volume
3
http://library.link/vocab/subjectName
  • Capillaries
  • Microcirculation
  • Extracellular fluid
  • Lymphatics
  • Edema
  • Capillary Permeability
Target audience
  • adult
  • specialized
Label
Capillary fluid exchange : regulation, functions, and pathology, Joshua Scallan, Virgina H. Huxley, and Ronald J. Korthuis, (electronic book)
Instantiates
Publication
Note
Part of: 'Colloquium digital library of life sciences'
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references (p. 63-86)
Color
multicolored
Contents
  • 1. Fluid movement across the endothelial barrier -- The starling equation -- Hydraulic conductivity -- Assessment of diffusive permeability -- Convective solute transport across the microvascular walls -- Capillary the morphology varies among organs -- Transendothelial filtration modifies vascular function --
  • 2. The interstitium -- Composition, structure and three-dimensional organization of the extracellular matrix in the interstitial spaces -- Solute exclusion and osmotic amplification -- Compliance and hydraulic conductance in the extracellular matrix -- Fluid flow in the interstitium modifies the function of tissue cells --
  • 3. The lymphatic vasculature -- Anatomy and nomenclature of the lymphatic vasculature -- Lymph formation -- Interstitial fluid pressure and its influence on lymph flow -- Lymphatic solute permeability -- Propulsion of lymph by the lymphatic muscle pump -- Lymphangiogenesis -- Tumors and lymphatic metastasis -- Cessation of lymph flow and its immunological consequences --
  • 4. Pathophysiology of edema formation -- The margin of safety against edema formation, edema safety factors -- Vasogenic edema -- Hypoproteinemia -- Permeability edema and inflammation -- Neurogenic inflammation -- Myxedema -- Lymphedema -- References
Dimensions
unknown
Extent
1 electronic text (viii, 86 p. : ill.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615040674
Level of compression
unknown
Other physical details
digital file. ;
Quality assurance targets
unknown
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader
Label
Capillary fluid exchange : regulation, functions, and pathology, Joshua Scallan, Virgina H. Huxley, and Ronald J. Korthuis, (electronic book)
Publication
Note
Part of: 'Colloquium digital library of life sciences'
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references (p. 63-86)
Color
multicolored
Contents
  • 1. Fluid movement across the endothelial barrier -- The starling equation -- Hydraulic conductivity -- Assessment of diffusive permeability -- Convective solute transport across the microvascular walls -- Capillary the morphology varies among organs -- Transendothelial filtration modifies vascular function --
  • 2. The interstitium -- Composition, structure and three-dimensional organization of the extracellular matrix in the interstitial spaces -- Solute exclusion and osmotic amplification -- Compliance and hydraulic conductance in the extracellular matrix -- Fluid flow in the interstitium modifies the function of tissue cells --
  • 3. The lymphatic vasculature -- Anatomy and nomenclature of the lymphatic vasculature -- Lymph formation -- Interstitial fluid pressure and its influence on lymph flow -- Lymphatic solute permeability -- Propulsion of lymph by the lymphatic muscle pump -- Lymphangiogenesis -- Tumors and lymphatic metastasis -- Cessation of lymph flow and its immunological consequences --
  • 4. Pathophysiology of edema formation -- The margin of safety against edema formation, edema safety factors -- Vasogenic edema -- Hypoproteinemia -- Permeability edema and inflammation -- Neurogenic inflammation -- Myxedema -- Lymphedema -- References
Dimensions
unknown
Extent
1 electronic text (viii, 86 p. : ill.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615040674
Level of compression
unknown
Other physical details
digital file. ;
Quality assurance targets
unknown
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader

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