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The Resource Cerebral ischemic reperfusion injuries (CIRI) : bench research and clinical implications, Weijian Jiang, Wengui Yu, Yan Qu, Zhongsong Shi, Benyan Luo, John H. Zhang, editors

Cerebral ischemic reperfusion injuries (CIRI) : bench research and clinical implications, Weijian Jiang, Wengui Yu, Yan Qu, Zhongsong Shi, Benyan Luo, John H. Zhang, editors

Editor
Contributor
Summary
This volume is focused on subjects related to cerebral ischemia and reperfusion injuries after acute stroke. All chapters are selected from the Sixth Elite Stroke meeting named Pangu Stroke Conference and written by members of world leading laboratories of stroke studies. The contents cover both clinical and bench studies, from basic components of cerebral arterial system to clinical reperfusion injury cases, from reperfusion caused programmed cell death and astrocyte activation to oxidative stress and nitric oxide after reperfusion, from extracellular matrix and inflammation to a role of diabetes after reperfusion, from small artery disorders to collateral circulation and blood pressure control after reperfusion. Wei-Jian Jiang, Chairman of New Era Stroke Care and Research Institute of PLA Rocket Force General Hospital, Beijing, China. Wengui Yu, Professor and Director of Comprehensive Stroke & Cerebrovascular Center, University of California, Irvine Yan Qu, Professor and Director of Neurosurgery at the Second Affiliated Hospital of Air Force Medical University, Xi'an, China. Zhongsong Shi, Professor of Neurosurgery at Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. Ben-yan Luo, Professor and Chair of Neurology at the First Affiliated Hospital of Zhejiang University. John H. Zhang, Professor of Anesthesiology and Physiology at Loma Linda University School of Medicine, Loma Linda, CA, USA
Language
eng
Work
Publication
Extent
1 online resource (xvii, 259 pages)
Contents
  • Intro; Preface; Introduction; Recanalization-Related Injury; Safety and Efficacy of Late Recanalization; The Application of New Imaging Technique and Strategies; The Characteristics of Posterior Circulation Stroke; The Immune Regulation and Stroke; The Cerebral Venous System and Stroke; Contents; About the Editors; Chapter 1: Gelatinase-­Mediated Impairment of Microvascular Beds in Cerebral Ischemia and Reperfusion Injury; 1 Introduction; 2 Microvascular Beds and the Extracellular Matrix (ECM); 3 Gelatinases Mediate Impairment of Microvascular Beds in CIRI
  • 4 Activation of Gelatinases and Extravasation of tPA into Brain Parenchyma in CIRI-Induced Microvascular Bed Damage5 Early Inhibition of Gelatinases May Escalate Neuroprotection and Extend the tPA Therapeutic Window; References; Chapter 2: Characters of Ischemic Stroke and Recanalization Arteries; 1 Introduction; 2 Characters of the Ischemic Stroke; 2.1 Epidemiology and Risk Factors of Ischemic Stroke; 2.2 The Imaging and Diagnosis of Ischemic Stroke; 2.3 The Pathophysiology of Ischemic Stroke; 2.3.1 Excitotoxicity; 2.3.2 Inflammatory Response; 2.3.3 Apoptosis; 2.3.4 Autophagy
  • 2.3.5 Pyroptosis3 Artery Recanalization of Ischemic Stroke; 3.1 Intravenous Thrombolytic and Antiplatelet Therapy Treatment; 3.2 Endovascular Treatment for Acute Ischemic Stroke; 3.3 Antioxidant and Other Treatment; 4 Reperfusion Injury After Artery Recanalization; 5 Conclusion; References; Chapter 3: Cerebral Ischemic Reperfusion Injury (CIRI) Cases; 1 Case Description; 2 Discussion; References; Chapter 4: CIRI After Early Recanalization; 1 Hemorrhage Transformation (HT); 1.1 Mechanisms; 1.1.1 Oxidative Stress; 1.1.2 Neurovascular Unit Injury; 1.2 Predictive Imaging Markers
  • 1.2.1 Brain-Blood Barrier Permeability1.2.2 Postischemic Hyperperfusion; 2 Infarct Growth; 2.1 Mechanisms; 2.1.1 Apoptosis; 2.1.2 Neutrophil Infiltration and Immune Inflammation; 2.2 Predictive Imaging Markers; 2.2.1 No-Reflow Phenomenon; 2.2.2 Cerebral Neutrophil Recruitment; 2.2.3 Vascular Inflammation; 2.2.4 Postischemic Hyperperfusion; 3 Brain Edema; 3.1 Mechanisms and Edema Types; 3.1.1 Brain-Blood Barrier Damage and Vasogenic Edema; 3.1.2 Postischemic Hyperperfusion and Cytotoxic Edema; 4 Treatments; 4.1 Ischemic Conditioning Therapy; 4.1.1 Ischemic Preconditioning Therapy
  • 4.1.2 Ischemic Postconditioning Therapy4.2 Immunosuppressive Agents; 4.3 Hypothermia Treatment; 5 Conclusion; References; Chapter 5: Programmed Cell Death in CIRI; 1 Introduction; 2 Apoptotic Cell Death in CIRI; 2.1 Molecular Biology Mechanism of Apoptosis After Ischemic Stroke; 2.1.1 Molecules Related to Apoptosis of Neurons; Caspase Family; B-Cell Leukemia/Lymphoma 2 (Bcl-2) Family; Tumor Necrosis Factor Receptor (TNFR) Superfamily; Other Molecules; 2.2 Pathways Related to Apoptosis of CIRI; 2.2.1 Intrinsic Pathway; 2.2.2 Extrinsic Pathway; 2.3 Significance of Apoptosis in CIRI
Isbn
9783319901930
Instance
Label
Cerebral ischemic reperfusion injuries (CIRI) : bench research and clinical implications
Title
Cerebral ischemic reperfusion injuries (CIRI)
Title remainder
bench research and clinical implications
Statement of responsibility
Weijian Jiang, Wengui Yu, Yan Qu, Zhongsong Shi, Benyan Luo, John H. Zhang, editors
Contributor
Editor
Subject
Language
eng
Summary
This volume is focused on subjects related to cerebral ischemia and reperfusion injuries after acute stroke. All chapters are selected from the Sixth Elite Stroke meeting named Pangu Stroke Conference and written by members of world leading laboratories of stroke studies. The contents cover both clinical and bench studies, from basic components of cerebral arterial system to clinical reperfusion injury cases, from reperfusion caused programmed cell death and astrocyte activation to oxidative stress and nitric oxide after reperfusion, from extracellular matrix and inflammation to a role of diabetes after reperfusion, from small artery disorders to collateral circulation and blood pressure control after reperfusion. Wei-Jian Jiang, Chairman of New Era Stroke Care and Research Institute of PLA Rocket Force General Hospital, Beijing, China. Wengui Yu, Professor and Director of Comprehensive Stroke & Cerebrovascular Center, University of California, Irvine Yan Qu, Professor and Director of Neurosurgery at the Second Affiliated Hospital of Air Force Medical University, Xi'an, China. Zhongsong Shi, Professor of Neurosurgery at Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. Ben-yan Luo, Professor and Chair of Neurology at the First Affiliated Hospital of Zhejiang University. John H. Zhang, Professor of Anesthesiology and Physiology at Loma Linda University School of Medicine, Loma Linda, CA, USA
Member of
Cataloging source
GW5XE
Dewey number
616.8/1
Illustrations
illustrations
Index
no index present
LC call number
RC388.5
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Jiang, Weijian
  • Yu, Wengui
  • Qu, Yan
  • Shi, Zhongsong
  • Luo, Benyan
  • Zhang, J. H.
Series statement
Springer series in translational stroke research,
http://library.link/vocab/subjectName
  • Cerebral ischemia
  • Reperfusion injury
Label
Cerebral ischemic reperfusion injuries (CIRI) : bench research and clinical implications, Weijian Jiang, Wengui Yu, Yan Qu, Zhongsong Shi, Benyan Luo, John H. Zhang, editors
Instantiates
Publication
Antecedent source
unknown
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Intro; Preface; Introduction; Recanalization-Related Injury; Safety and Efficacy of Late Recanalization; The Application of New Imaging Technique and Strategies; The Characteristics of Posterior Circulation Stroke; The Immune Regulation and Stroke; The Cerebral Venous System and Stroke; Contents; About the Editors; Chapter 1: Gelatinase-­Mediated Impairment of Microvascular Beds in Cerebral Ischemia and Reperfusion Injury; 1 Introduction; 2 Microvascular Beds and the Extracellular Matrix (ECM); 3 Gelatinases Mediate Impairment of Microvascular Beds in CIRI
  • 4 Activation of Gelatinases and Extravasation of tPA into Brain Parenchyma in CIRI-Induced Microvascular Bed Damage5 Early Inhibition of Gelatinases May Escalate Neuroprotection and Extend the tPA Therapeutic Window; References; Chapter 2: Characters of Ischemic Stroke and Recanalization Arteries; 1 Introduction; 2 Characters of the Ischemic Stroke; 2.1 Epidemiology and Risk Factors of Ischemic Stroke; 2.2 The Imaging and Diagnosis of Ischemic Stroke; 2.3 The Pathophysiology of Ischemic Stroke; 2.3.1 Excitotoxicity; 2.3.2 Inflammatory Response; 2.3.3 Apoptosis; 2.3.4 Autophagy
  • 2.3.5 Pyroptosis3 Artery Recanalization of Ischemic Stroke; 3.1 Intravenous Thrombolytic and Antiplatelet Therapy Treatment; 3.2 Endovascular Treatment for Acute Ischemic Stroke; 3.3 Antioxidant and Other Treatment; 4 Reperfusion Injury After Artery Recanalization; 5 Conclusion; References; Chapter 3: Cerebral Ischemic Reperfusion Injury (CIRI) Cases; 1 Case Description; 2 Discussion; References; Chapter 4: CIRI After Early Recanalization; 1 Hemorrhage Transformation (HT); 1.1 Mechanisms; 1.1.1 Oxidative Stress; 1.1.2 Neurovascular Unit Injury; 1.2 Predictive Imaging Markers
  • 1.2.1 Brain-Blood Barrier Permeability1.2.2 Postischemic Hyperperfusion; 2 Infarct Growth; 2.1 Mechanisms; 2.1.1 Apoptosis; 2.1.2 Neutrophil Infiltration and Immune Inflammation; 2.2 Predictive Imaging Markers; 2.2.1 No-Reflow Phenomenon; 2.2.2 Cerebral Neutrophil Recruitment; 2.2.3 Vascular Inflammation; 2.2.4 Postischemic Hyperperfusion; 3 Brain Edema; 3.1 Mechanisms and Edema Types; 3.1.1 Brain-Blood Barrier Damage and Vasogenic Edema; 3.1.2 Postischemic Hyperperfusion and Cytotoxic Edema; 4 Treatments; 4.1 Ischemic Conditioning Therapy; 4.1.1 Ischemic Preconditioning Therapy
  • 4.1.2 Ischemic Postconditioning Therapy4.2 Immunosuppressive Agents; 4.3 Hypothermia Treatment; 5 Conclusion; References; Chapter 5: Programmed Cell Death in CIRI; 1 Introduction; 2 Apoptotic Cell Death in CIRI; 2.1 Molecular Biology Mechanism of Apoptosis After Ischemic Stroke; 2.1.1 Molecules Related to Apoptosis of Neurons; Caspase Family; B-Cell Leukemia/Lymphoma 2 (Bcl-2) Family; Tumor Necrosis Factor Receptor (TNFR) Superfamily; Other Molecules; 2.2 Pathways Related to Apoptosis of CIRI; 2.2.1 Intrinsic Pathway; 2.2.2 Extrinsic Pathway; 2.3 Significance of Apoptosis in CIRI
Dimensions
unknown
Extent
1 online resource (xvii, 259 pages)
File format
unknown
Form of item
online
Isbn
9783319901930
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-319-90194-7
Other physical details
illustrations (some color).
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • on1043756032
  • (OCoLC)1043756032
Label
Cerebral ischemic reperfusion injuries (CIRI) : bench research and clinical implications, Weijian Jiang, Wengui Yu, Yan Qu, Zhongsong Shi, Benyan Luo, John H. Zhang, editors
Publication
Antecedent source
unknown
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Intro; Preface; Introduction; Recanalization-Related Injury; Safety and Efficacy of Late Recanalization; The Application of New Imaging Technique and Strategies; The Characteristics of Posterior Circulation Stroke; The Immune Regulation and Stroke; The Cerebral Venous System and Stroke; Contents; About the Editors; Chapter 1: Gelatinase-­Mediated Impairment of Microvascular Beds in Cerebral Ischemia and Reperfusion Injury; 1 Introduction; 2 Microvascular Beds and the Extracellular Matrix (ECM); 3 Gelatinases Mediate Impairment of Microvascular Beds in CIRI
  • 4 Activation of Gelatinases and Extravasation of tPA into Brain Parenchyma in CIRI-Induced Microvascular Bed Damage5 Early Inhibition of Gelatinases May Escalate Neuroprotection and Extend the tPA Therapeutic Window; References; Chapter 2: Characters of Ischemic Stroke and Recanalization Arteries; 1 Introduction; 2 Characters of the Ischemic Stroke; 2.1 Epidemiology and Risk Factors of Ischemic Stroke; 2.2 The Imaging and Diagnosis of Ischemic Stroke; 2.3 The Pathophysiology of Ischemic Stroke; 2.3.1 Excitotoxicity; 2.3.2 Inflammatory Response; 2.3.3 Apoptosis; 2.3.4 Autophagy
  • 2.3.5 Pyroptosis3 Artery Recanalization of Ischemic Stroke; 3.1 Intravenous Thrombolytic and Antiplatelet Therapy Treatment; 3.2 Endovascular Treatment for Acute Ischemic Stroke; 3.3 Antioxidant and Other Treatment; 4 Reperfusion Injury After Artery Recanalization; 5 Conclusion; References; Chapter 3: Cerebral Ischemic Reperfusion Injury (CIRI) Cases; 1 Case Description; 2 Discussion; References; Chapter 4: CIRI After Early Recanalization; 1 Hemorrhage Transformation (HT); 1.1 Mechanisms; 1.1.1 Oxidative Stress; 1.1.2 Neurovascular Unit Injury; 1.2 Predictive Imaging Markers
  • 1.2.1 Brain-Blood Barrier Permeability1.2.2 Postischemic Hyperperfusion; 2 Infarct Growth; 2.1 Mechanisms; 2.1.1 Apoptosis; 2.1.2 Neutrophil Infiltration and Immune Inflammation; 2.2 Predictive Imaging Markers; 2.2.1 No-Reflow Phenomenon; 2.2.2 Cerebral Neutrophil Recruitment; 2.2.3 Vascular Inflammation; 2.2.4 Postischemic Hyperperfusion; 3 Brain Edema; 3.1 Mechanisms and Edema Types; 3.1.1 Brain-Blood Barrier Damage and Vasogenic Edema; 3.1.2 Postischemic Hyperperfusion and Cytotoxic Edema; 4 Treatments; 4.1 Ischemic Conditioning Therapy; 4.1.1 Ischemic Preconditioning Therapy
  • 4.1.2 Ischemic Postconditioning Therapy4.2 Immunosuppressive Agents; 4.3 Hypothermia Treatment; 5 Conclusion; References; Chapter 5: Programmed Cell Death in CIRI; 1 Introduction; 2 Apoptotic Cell Death in CIRI; 2.1 Molecular Biology Mechanism of Apoptosis After Ischemic Stroke; 2.1.1 Molecules Related to Apoptosis of Neurons; Caspase Family; B-Cell Leukemia/Lymphoma 2 (Bcl-2) Family; Tumor Necrosis Factor Receptor (TNFR) Superfamily; Other Molecules; 2.2 Pathways Related to Apoptosis of CIRI; 2.2.1 Intrinsic Pathway; 2.2.2 Extrinsic Pathway; 2.3 Significance of Apoptosis in CIRI
Dimensions
unknown
Extent
1 online resource (xvii, 259 pages)
File format
unknown
Form of item
online
Isbn
9783319901930
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-319-90194-7
Other physical details
illustrations (some color).
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • on1043756032
  • (OCoLC)1043756032

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