Coverart for item
The Resource Creating connections in the developing brain : mechanisms regulating corpus callosum development, Ilan Gobius and Linda Richards, (electronic book)

Creating connections in the developing brain : mechanisms regulating corpus callosum development, Ilan Gobius and Linda Richards, (electronic book)

Label
Creating connections in the developing brain : mechanisms regulating corpus callosum development
Title
Creating connections in the developing brain
Title remainder
mechanisms regulating corpus callosum development
Statement of responsibility
Ilan Gobius and Linda Richards
Creator
Contributor
Subject
Language
eng
Summary
The corpus callosum is the largest fibre tract in the human brain and subserves many of the brain's higher-order functions. Disconnection syndromes resulting from surgical ablation, developmental absence (agenesis of the corpus callosum), disease, or injury of the corpus callosum can have profound consequences on cognition. Callosal development involves an intricate series of sequential and concurrent processes, including telencephalic induction, midline tissue patterning, production and specification of callosal neurons. In addition, axon extension and long-range axonal guidance from one hemisphere to the other are required for functional circuit formation in the contralateral hemisphere. Genetic or traumatic disruption to any part of this sequence is pathogenic. Understanding the key processes involved in callosal development is the first step in providing both better neuropsychological outcomes and improved diagnostic and prognostic tools for congenital disconnection syndromes in the future
Member of
Cataloging source
CaBNVSL
http://library.link/vocab/creatorName
Gobius, Ilan
Dewey number
612.825
Illustrations
illustrations
Index
no index present
LC call number
QP382.2
LC item number
.G633 2011
Literary form
non fiction
Nature of contents
  • dictionaries
  • abstracts summaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
Richards, Linda J.
Series statement
Colloquium series on the developing brain
Series volume
2
http://library.link/vocab/subjectName
Corpus callosum
Target audience
specialized
Label
Creating connections in the developing brain : mechanisms regulating corpus callosum development, Ilan Gobius and Linda Richards, (electronic book)
Instantiates
Publication
Bibliography note
Includes bibliographical references (p. 31-39)
Color
multicolored
Contents
  • 1. Introduction --
  • 2. Formation of the telencephalic hemispheres --
  • 3. Midline tissue patterning: preparing the callosal substrate -- 3.1 Formation and development of the interhemispheric midline -- 3.1.1 Holoprosencephaly: how initial telencephalic midline formation affects callosal development -- 3.2 Interhemispheric midline fusion --
  • 4. Specification of callosal projection neurons within the neocortex and cingulate cortex -- 4.1 The neocortex -- 4.1.1 Satb2 specifies neocortical callosal projection neurons -- 4.2 The cingulate cortex -- 4.2.1 Emx2 regulates specification of cingulate pioneer projection neurons --
  • 5. Establishing the callosal tract -- 5.1 Axon extension and medial turning within the cortex -- 5.2 Axon-axon interactions: fasciculation --
  • 6. Navigating the midline: growth of the corpus callosum across the interhemispheric midline -- 6.1 Cellular architecture of the interhemispheric midline -- 6.1.1 Astrogliogenesis in the telencephalon -- 6.1.2 Malformations in the glial wedge and indusium griseum glia are associated with agenesis of the corpus callosum -- 6.1.3 The glial wedge -- 6.1.4 The indusium griseum glia -- 6.1.5 The subcallosal sling/midline corridor -- 6.2 Axonal guidance mechanisms at the interhemispheric midline -- 6.2.1 Semaphorin signalling -- 6.2.2 Slit signalling -- 6.2.3 Draxin signalling -- 6.2.4 Wnt signalling --
  • 7. Contralateral targeting of callosal axons: the role of neuronal activity --
  • 8. Conclusion -- References
Control code
201107DBR002
Dimensions
unknown
Extent
1 electronic text (viii, 39 p.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615040797
Other physical details
ill., digital file
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader
Label
Creating connections in the developing brain : mechanisms regulating corpus callosum development, Ilan Gobius and Linda Richards, (electronic book)
Publication
Bibliography note
Includes bibliographical references (p. 31-39)
Color
multicolored
Contents
  • 1. Introduction --
  • 2. Formation of the telencephalic hemispheres --
  • 3. Midline tissue patterning: preparing the callosal substrate -- 3.1 Formation and development of the interhemispheric midline -- 3.1.1 Holoprosencephaly: how initial telencephalic midline formation affects callosal development -- 3.2 Interhemispheric midline fusion --
  • 4. Specification of callosal projection neurons within the neocortex and cingulate cortex -- 4.1 The neocortex -- 4.1.1 Satb2 specifies neocortical callosal projection neurons -- 4.2 The cingulate cortex -- 4.2.1 Emx2 regulates specification of cingulate pioneer projection neurons --
  • 5. Establishing the callosal tract -- 5.1 Axon extension and medial turning within the cortex -- 5.2 Axon-axon interactions: fasciculation --
  • 6. Navigating the midline: growth of the corpus callosum across the interhemispheric midline -- 6.1 Cellular architecture of the interhemispheric midline -- 6.1.1 Astrogliogenesis in the telencephalon -- 6.1.2 Malformations in the glial wedge and indusium griseum glia are associated with agenesis of the corpus callosum -- 6.1.3 The glial wedge -- 6.1.4 The indusium griseum glia -- 6.1.5 The subcallosal sling/midline corridor -- 6.2 Axonal guidance mechanisms at the interhemispheric midline -- 6.2.1 Semaphorin signalling -- 6.2.2 Slit signalling -- 6.2.3 Draxin signalling -- 6.2.4 Wnt signalling --
  • 7. Contralateral targeting of callosal axons: the role of neuronal activity --
  • 8. Conclusion -- References
Control code
201107DBR002
Dimensions
unknown
Extent
1 electronic text (viii, 39 p.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615040797
Other physical details
ill., digital file
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader

Library Locations

Processing Feedback ...