The Resource Discovery and development of therapeutics from natural products against neglected tropical diseases, edited by Goutam Brahmachari
Discovery and development of therapeutics from natural products against neglected tropical diseases, edited by Goutam Brahmachari
Resource Information
The item Discovery and development of therapeutics from natural products against neglected tropical diseases, edited by Goutam Brahmachari represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Liverpool.This item is available to borrow from 1 library branch.
Resource Information
The item Discovery and development of therapeutics from natural products against neglected tropical diseases, edited by Goutam Brahmachari represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Liverpool.
This item is available to borrow from 1 library branch.
- Summary
- Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases
- Language
- eng
- Extent
- 1 online resource.
- Contents
-
- Front Cover; Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases; Copyright Page; Dedication; Contents; List of Contributors; Editor Biography; Foreword; Preface; 1 Therapeutics from natural products against neglected tropical diseases: an overview; 1.1 Introduction; 1.2 An overview of the book; 1.3 Concluding remarks; 2 Marine natural products as strategic prototypes in the development of a new generation of antimalarial agents; 2.1 Introduction; 2.2 Antimalarial marine natural products; 2.2.1 Phenolic compounds and polyketides
- 2.2.2 Terpenoids2.2.3 Endoperoxides and polyethers; 2.2.4 Alkaloids; 2.2.5 Peptides and depsipeptides; 2.2.6 Phosphotriesters; 2.3 Concluding remarks; List of abbreviations; References; Further reading; 3 Sesquiterpene lactones: a versatile class of structurally diverse natural products and their semisynthetic analogs as pot...; 3.1 Introduction; 3.2 Antimalarial potential of plant derived sesquiterpene lactones; 3.2.1 Artemisinin and its C-12 oxa (ether/ester) derivatives; 3.2.1.1 Synthesis of C-12 carba-derivatives of artemisinin
- 3.2.1.2 Synthesis of C-13 substituted derivatives of artemisinin from artemisitene3.2.1.3 Artemisinin dimers, trimers, and tetramers: novel leads in drug discovery; 3.2.1.4 Synthesis of artemisinin dimers; 3.2.1.5 Synthesis of artemisinin trimers and tetramers; 3.2.2 Germacranolides, guaianolides, and pseudoguiainolides antimalarials SLs; 3.2.2.1 Germacranolides; 3.2.2.2 Guaianolides and pseudoguaianolides; 3.2.3 Miscellaneous antimalarial sesquiterpene lactones; 3.3 Structural-activity relationships of sesquiterpene lactones; 3.4 Concluding remarks; Acknowledgments; List of abbreviations
- 4.6 Natural sources of quinoline alkaloids with antiparasitic activity4.7 Synthetic efforts for targeted quinoline compounds; 4.7.1 Synthesis of polyfunctionalized quinolines from unsubstituted anilines: Route A; 4.7.2 Synthesis of polyfunctionalized quinolines from ortho-substituted anilines: Route B; 4.8 Quinoline compounds as antitrypanosomal agents; 4.8.1 Simple polyfunctionalized quinolines; 4.8.2 Polycyclic quinoline molecules; 4.9 Concluding remarks; Acknowledgment; List of abbreviations; References; Further reading
- Isbn
- 9780128157237
- Label
- Discovery and development of therapeutics from natural products against neglected tropical diseases
- Title
- Discovery and development of therapeutics from natural products against neglected tropical diseases
- Statement of responsibility
- edited by Goutam Brahmachari
- Language
- eng
- Summary
- Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases
- Cataloging source
- N$T
- Dewey number
- 616.462061
- Index
- no index present
- LC call number
- RC661.A1
- Literary form
- non fiction
- Nature of contents
- dictionaries
- http://library.link/vocab/relatedWorkOrContributorName
- Brahmachari, Goutam
- Series statement
- Natural product drug discovery
- http://library.link/vocab/subjectName
-
- Hypoglycemic agents
- Materia medica.
- Label
- Discovery and development of therapeutics from natural products against neglected tropical diseases, edited by Goutam Brahmachari
- Antecedent source
- unknown
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
-
- Front Cover; Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases; Copyright Page; Dedication; Contents; List of Contributors; Editor Biography; Foreword; Preface; 1 Therapeutics from natural products against neglected tropical diseases: an overview; 1.1 Introduction; 1.2 An overview of the book; 1.3 Concluding remarks; 2 Marine natural products as strategic prototypes in the development of a new generation of antimalarial agents; 2.1 Introduction; 2.2 Antimalarial marine natural products; 2.2.1 Phenolic compounds and polyketides
- 2.2.2 Terpenoids2.2.3 Endoperoxides and polyethers; 2.2.4 Alkaloids; 2.2.5 Peptides and depsipeptides; 2.2.6 Phosphotriesters; 2.3 Concluding remarks; List of abbreviations; References; Further reading; 3 Sesquiterpene lactones: a versatile class of structurally diverse natural products and their semisynthetic analogs as pot...; 3.1 Introduction; 3.2 Antimalarial potential of plant derived sesquiterpene lactones; 3.2.1 Artemisinin and its C-12 oxa (ether/ester) derivatives; 3.2.1.1 Synthesis of C-12 carba-derivatives of artemisinin
- 3.2.1.2 Synthesis of C-13 substituted derivatives of artemisinin from artemisitene3.2.1.3 Artemisinin dimers, trimers, and tetramers: novel leads in drug discovery; 3.2.1.4 Synthesis of artemisinin dimers; 3.2.1.5 Synthesis of artemisinin trimers and tetramers; 3.2.2 Germacranolides, guaianolides, and pseudoguiainolides antimalarials SLs; 3.2.2.1 Germacranolides; 3.2.2.2 Guaianolides and pseudoguaianolides; 3.2.3 Miscellaneous antimalarial sesquiterpene lactones; 3.3 Structural-activity relationships of sesquiterpene lactones; 3.4 Concluding remarks; Acknowledgments; List of abbreviations
- 4.6 Natural sources of quinoline alkaloids with antiparasitic activity4.7 Synthetic efforts for targeted quinoline compounds; 4.7.1 Synthesis of polyfunctionalized quinolines from unsubstituted anilines: Route A; 4.7.2 Synthesis of polyfunctionalized quinolines from ortho-substituted anilines: Route B; 4.8 Quinoline compounds as antitrypanosomal agents; 4.8.1 Simple polyfunctionalized quinolines; 4.8.2 Polycyclic quinoline molecules; 4.9 Concluding remarks; Acknowledgment; List of abbreviations; References; Further reading
- Dimensions
- unknown
- Extent
- 1 online resource.
- File format
- unknown
- Form of item
- online
- Isbn
- 9780128157237
- Level of compression
- unknown
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Quality assurance targets
- not applicable
- Reformatting quality
- unknown
- Sound
- unknown sound
- Specific material designation
- remote
- Label
- Discovery and development of therapeutics from natural products against neglected tropical diseases, edited by Goutam Brahmachari
- Antecedent source
- unknown
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
-
- Front Cover; Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases; Copyright Page; Dedication; Contents; List of Contributors; Editor Biography; Foreword; Preface; 1 Therapeutics from natural products against neglected tropical diseases: an overview; 1.1 Introduction; 1.2 An overview of the book; 1.3 Concluding remarks; 2 Marine natural products as strategic prototypes in the development of a new generation of antimalarial agents; 2.1 Introduction; 2.2 Antimalarial marine natural products; 2.2.1 Phenolic compounds and polyketides
- 2.2.2 Terpenoids2.2.3 Endoperoxides and polyethers; 2.2.4 Alkaloids; 2.2.5 Peptides and depsipeptides; 2.2.6 Phosphotriesters; 2.3 Concluding remarks; List of abbreviations; References; Further reading; 3 Sesquiterpene lactones: a versatile class of structurally diverse natural products and their semisynthetic analogs as pot...; 3.1 Introduction; 3.2 Antimalarial potential of plant derived sesquiterpene lactones; 3.2.1 Artemisinin and its C-12 oxa (ether/ester) derivatives; 3.2.1.1 Synthesis of C-12 carba-derivatives of artemisinin
- 3.2.1.2 Synthesis of C-13 substituted derivatives of artemisinin from artemisitene3.2.1.3 Artemisinin dimers, trimers, and tetramers: novel leads in drug discovery; 3.2.1.4 Synthesis of artemisinin dimers; 3.2.1.5 Synthesis of artemisinin trimers and tetramers; 3.2.2 Germacranolides, guaianolides, and pseudoguiainolides antimalarials SLs; 3.2.2.1 Germacranolides; 3.2.2.2 Guaianolides and pseudoguaianolides; 3.2.3 Miscellaneous antimalarial sesquiterpene lactones; 3.3 Structural-activity relationships of sesquiterpene lactones; 3.4 Concluding remarks; Acknowledgments; List of abbreviations
- 4.6 Natural sources of quinoline alkaloids with antiparasitic activity4.7 Synthetic efforts for targeted quinoline compounds; 4.7.1 Synthesis of polyfunctionalized quinolines from unsubstituted anilines: Route A; 4.7.2 Synthesis of polyfunctionalized quinolines from ortho-substituted anilines: Route B; 4.8 Quinoline compounds as antitrypanosomal agents; 4.8.1 Simple polyfunctionalized quinolines; 4.8.2 Polycyclic quinoline molecules; 4.9 Concluding remarks; Acknowledgment; List of abbreviations; References; Further reading
- Dimensions
- unknown
- Extent
- 1 online resource.
- File format
- unknown
- Form of item
- online
- Isbn
- 9780128157237
- Level of compression
- unknown
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Quality assurance targets
- not applicable
- Reformatting quality
- unknown
- Sound
- unknown sound
- Specific material designation
- remote
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.liverpool.ac.uk/portal/Discovery-and-development-of-therapeutics-from/ObfBnay6DV0/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.liverpool.ac.uk/portal/Discovery-and-development-of-therapeutics-from/ObfBnay6DV0/">Discovery and development of therapeutics from natural products against neglected tropical diseases, edited by Goutam Brahmachari</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.liverpool.ac.uk/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.liverpool.ac.uk/">University of Liverpool</a></span></span></span></span></div>
