The Resource Drug class review : final report update 5, HMG-CoA reductase inhibitors (statins) and fixed-dose combination products containing a statin, M.E. Beth Smith ... [et al.] ; Drug Effectiveness Review Project, Oregon Evidence-based Practice Center, Oregon Health & Science University, (electronic book)

Drug class review : final report update 5, HMG-CoA reductase inhibitors (statins) and fixed-dose combination products containing a statin, M.E. Beth Smith ... [et al.] ; Drug Effectiveness Review Project, Oregon Evidence-based Practice Center, Oregon Health & Science University, (electronic book)

Label
Drug class review : final report update 5, HMG-CoA reductase inhibitors (statins) and fixed-dose combination products containing a statin
Title
Drug class review
Title remainder
final report update 5
Title part
HMG-CoA reductase inhibitors (statins) and fixed-dose combination products containing a statin
Statement of responsibility
M.E. Beth Smith ... [et al.] ; Drug Effectiveness Review Project, Oregon Evidence-based Practice Center, Oregon Health & Science University
Title variation
HMG-CoA reductase inhibitors (statins) and fixed-dose combination products containing a statin
Contributor
Subject
Language
  • eng
  • eng
Summary
In the United States, coronary heart disease and cardiovascular disease account for nearly 40% of all deaths each year. Coronary heart disease continues to be the leading cause of mortality and a significant cause of morbidity among North Americans. In 2006, coronary heart disease claimed 607 000 lives, translating into about 1 out of every 5 deaths in the United States. High levels of cholesterol, or hypercholesterolemia, are an important risk factor for coronary heart disease. The 3-hydroxy-3-methylglutaryl-coenzyme (HMG-CoA) reductase inhibitors, also known as statins, are the most effective class of drugs for lowering serum low-density lipoprotein cholesterol concentrations. They are first-line agents for patients who require drug therapy to reduce serum low-density lipoprotein cholesterol concentrations. The purpose of this review is to compare the benefits and harms of different statins in adults and children with hypercholesterolemia
Member of
Additional physical form
Issued also online.
Cataloging source
DNLM
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Smith, M. E. Beth.
  • Drug Effectiveness Review Project.
  • Oregon Health & Science University
  • Oregon Health & Science University.
Series statement
Drug class reviews
http://library.link/vocab/subjectName
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Hypercholesterolemia
  • Coronary Disease
  • Drug Evaluation
  • Evidence-Based Medicine
  • Clinical Trials as Topic
  • United States
Label
Drug class review : final report update 5, HMG-CoA reductase inhibitors (statins) and fixed-dose combination products containing a statin, M.E. Beth Smith ... [et al.] ; Drug Effectiveness Review Project, Oregon Evidence-based Practice Center, Oregon Health & Science University, (electronic book)
Instantiates
Publication
Bibliography note
Includes bibliographical references
Control code
1554747
Dimensions
unknown
Form of item
online
Specific material designation
remote
Label
Drug class review : final report update 5, HMG-CoA reductase inhibitors (statins) and fixed-dose combination products containing a statin, M.E. Beth Smith ... [et al.] ; Drug Effectiveness Review Project, Oregon Evidence-based Practice Center, Oregon Health & Science University, (electronic book)
Publication
Bibliography note
Includes bibliographical references
Control code
1554747
Dimensions
unknown
Form of item
online
Specific material designation
remote

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