Coverart for item
The Resource Drug-induced liver toxicity, edited by Minjun Chen, Yvonne Will

Drug-induced liver toxicity, edited by Minjun Chen, Yvonne Will

Label
Drug-induced liver toxicity
Title
Drug-induced liver toxicity
Statement of responsibility
edited by Minjun Chen, Yvonne Will
Contributor
Editor
Subject
Genre
Language
eng
Member of
Cataloging source
RML
Dewey number
616.3/62
Illustrations
illustrations
Index
index present
LC call number
RC848.H48
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Chen, Minjun
  • Will, Yvonne
Series statement
Methods in pharmacology and toxicology,
http://library.link/vocab/subjectName
  • Hepatotoxicology
  • Chemical and Drug Induced Liver Injury
  • Drug Evaluation
  • Toxicity Tests
Label
Drug-induced liver toxicity, edited by Minjun Chen, Yvonne Will
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Quantitative structure-activity relationship models for predicting risk of drug-induced liver injury in humans
  • Huixiao Hong, Jieqiang Zhu, Minjun Chen, Ping Gong, Chaoyang Zhang, and Weida Tong
  • Introduction to DILIsym® software, a mechanistic mathematical representation of drug-induced liver injury
  • Christina Battista, Brett A. Howell, Scott Q. Siler, and Paul B. Watkins
  • Prediction of human liver toxicity using in vitro assays : limitations and opportunities
  • Franck A. Atienzar and Jean-Marie Nicolas
  • Use of liver-derived cell lines for the study of drug-induced liver injury
  • Zhen Ren, Si Chen, Baitang Ning, and Lei Guo
  • Evaluation of drug-induced liver injuries (DILI) with human hepatocytes : scientific rationale and experimental approaches
  • Albert P. Li
  • Overview of mechanisms of drug-induced liver injury (DILI) and key challenges in DILI research
  • Status and use of induced pluripotent stem cells (iPSCs) in toxicity testing
  • Min Wei Wong, Chris S. Pridgeon, Constanze Schlott, B. Kevin Park, and Christopher E.P. Goldring
  • Engineered human liver cocultures for investigating drug-induced liver injury
  • Chase P. Monckton and Salman R. Khetani
  • Status and future of 3D cell culture in toxicity testing
  • Monicah A. Otieno, Jinping Gan, and William Proctor
  • Reactive metabolite assessment in drug discovery and development in support of safe drug design
  • Axel Pähler
  • In vitro assessment of mitochondrial toxicity to predict drug-induced liver injury
  • Mathieu Porceddu, Nelly Buron, Pierre Rustin, Bernard Fromenty, and Annie Borgne-Sanchez
  • Nabil Noureddin and Neil Kaplowitz
  • Bile salt export pump : drug-induced liver injury and assessment approaches
  • Ruitang Deng
  • High content screening for prediction of human drug-induced liver injury
  • Mikael Persson
  • Interpretation, integration, and implementation of in vitro assay data : the predictive toxicity challenge
  • Deborah S. Light, Michael D. Aleo, and J. Gerry Kenna
  • Perspectives on the regulatory and clinical science of drug-induced liver injury (DILI)
  • Mark I. Avigan and Monica A. Muñoz
  • Regulatory toxicological studies : identifying drug-induced liver injury using nonclinical studies
  • Imran Khan and Elizabeth Hausner
  • Detection, elimination, mitigation, and prediction of drug-induced liver injury in drug discovery
  • Hy's law and eDISH for clinical studies
  • John Senior and Ted Guo
  • Variability in baseline liver test values in clinical trials : challenges in enhancing drug-induced liver injury assessment in subjects with liver disease
  • Bereket Tesfaldet, Gyorgy Csako, Tejas Patel, Md Shamsuzzaman, and Eileen Navarro Almario
  • Postmarketing surveillance of drug-induced liver injury
  • S. Christopher Jones, Cindy Kortepeter, and Allen D. Brinker
  • Host risk modifiers in idiosyncratic drug-induced liver injury (DILI) and its interplay with drug properties
  • Camilla Stephens, M. Isabel Lucena, and Raúl J. Andrade
  • Human leukocyte antigen (HLA) and other genetic risk factors in drug-induced liver injury (DILI)
  • Ann K. Daly
  • Francois Pognan
  • Immune mechanisms in drug-induced liver injury
  • Hartmut Jaeschke and Dean J. Naisbitt
  • Translational and mechanistic biomarkers of drug-induced liver injury - candidates and qualification strategies
  • Daniel J. Antoine
  • Causality assessment methods in drug-induced liver injury
  • Rolf Teschke and Gaby Danan
  • Circulating microRNAs as novel biomarkers of drug-induced liver injury in humans
  • Julian Krauskopf, Jos C. Kleinjans, and Theo M. de Kok
  • Systems microscopy approaches in unraveling and predicting drug-induced liver injury (DILI)
  • Marije Niemeijer, Steven Hiemstra, Steven Wink, Wouter den Hollander, Bas ter Braak, and Bob van de Water
  • Drug-induced liver injury (DILI) classification and its application on human DILI risk prediction
  • Noninvasive preclinical and clinical imaging of liver transporter function relevant to drug-induced liver injury
  • J. Gerry Kenna, John C. Waterton, Andreas Baudy, Aleksandra Galetin, Catherine D. G. Hines, Paul Hockings, Manishkumar Patel, Daniel Scotcher, Steven Sourbron, Sabina Ziemian, and Gunnar Schuetz
  • Shraddha Thakkar, Minjun Chen, Huixiao Hong, Zhichao Liu, Hong Fang, and Weida Tong
  • Physicochemical properties and structural alerts
  • Lilia Fisk, Nigel Greene, and Russ Naven
Control code
SPRP1029201431
Dimensions
unknown
Extent
1 online resource (xx, 667 pages)
File format
unknown
Form of item
online
Isbn
9781493976768
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color) ;
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • on1029201431
  • (OCoLC)1029201431
Label
Drug-induced liver toxicity, edited by Minjun Chen, Yvonne Will
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Quantitative structure-activity relationship models for predicting risk of drug-induced liver injury in humans
  • Huixiao Hong, Jieqiang Zhu, Minjun Chen, Ping Gong, Chaoyang Zhang, and Weida Tong
  • Introduction to DILIsym® software, a mechanistic mathematical representation of drug-induced liver injury
  • Christina Battista, Brett A. Howell, Scott Q. Siler, and Paul B. Watkins
  • Prediction of human liver toxicity using in vitro assays : limitations and opportunities
  • Franck A. Atienzar and Jean-Marie Nicolas
  • Use of liver-derived cell lines for the study of drug-induced liver injury
  • Zhen Ren, Si Chen, Baitang Ning, and Lei Guo
  • Evaluation of drug-induced liver injuries (DILI) with human hepatocytes : scientific rationale and experimental approaches
  • Albert P. Li
  • Overview of mechanisms of drug-induced liver injury (DILI) and key challenges in DILI research
  • Status and use of induced pluripotent stem cells (iPSCs) in toxicity testing
  • Min Wei Wong, Chris S. Pridgeon, Constanze Schlott, B. Kevin Park, and Christopher E.P. Goldring
  • Engineered human liver cocultures for investigating drug-induced liver injury
  • Chase P. Monckton and Salman R. Khetani
  • Status and future of 3D cell culture in toxicity testing
  • Monicah A. Otieno, Jinping Gan, and William Proctor
  • Reactive metabolite assessment in drug discovery and development in support of safe drug design
  • Axel Pähler
  • In vitro assessment of mitochondrial toxicity to predict drug-induced liver injury
  • Mathieu Porceddu, Nelly Buron, Pierre Rustin, Bernard Fromenty, and Annie Borgne-Sanchez
  • Nabil Noureddin and Neil Kaplowitz
  • Bile salt export pump : drug-induced liver injury and assessment approaches
  • Ruitang Deng
  • High content screening for prediction of human drug-induced liver injury
  • Mikael Persson
  • Interpretation, integration, and implementation of in vitro assay data : the predictive toxicity challenge
  • Deborah S. Light, Michael D. Aleo, and J. Gerry Kenna
  • Perspectives on the regulatory and clinical science of drug-induced liver injury (DILI)
  • Mark I. Avigan and Monica A. Muñoz
  • Regulatory toxicological studies : identifying drug-induced liver injury using nonclinical studies
  • Imran Khan and Elizabeth Hausner
  • Detection, elimination, mitigation, and prediction of drug-induced liver injury in drug discovery
  • Hy's law and eDISH for clinical studies
  • John Senior and Ted Guo
  • Variability in baseline liver test values in clinical trials : challenges in enhancing drug-induced liver injury assessment in subjects with liver disease
  • Bereket Tesfaldet, Gyorgy Csako, Tejas Patel, Md Shamsuzzaman, and Eileen Navarro Almario
  • Postmarketing surveillance of drug-induced liver injury
  • S. Christopher Jones, Cindy Kortepeter, and Allen D. Brinker
  • Host risk modifiers in idiosyncratic drug-induced liver injury (DILI) and its interplay with drug properties
  • Camilla Stephens, M. Isabel Lucena, and Raúl J. Andrade
  • Human leukocyte antigen (HLA) and other genetic risk factors in drug-induced liver injury (DILI)
  • Ann K. Daly
  • Francois Pognan
  • Immune mechanisms in drug-induced liver injury
  • Hartmut Jaeschke and Dean J. Naisbitt
  • Translational and mechanistic biomarkers of drug-induced liver injury - candidates and qualification strategies
  • Daniel J. Antoine
  • Causality assessment methods in drug-induced liver injury
  • Rolf Teschke and Gaby Danan
  • Circulating microRNAs as novel biomarkers of drug-induced liver injury in humans
  • Julian Krauskopf, Jos C. Kleinjans, and Theo M. de Kok
  • Systems microscopy approaches in unraveling and predicting drug-induced liver injury (DILI)
  • Marije Niemeijer, Steven Hiemstra, Steven Wink, Wouter den Hollander, Bas ter Braak, and Bob van de Water
  • Drug-induced liver injury (DILI) classification and its application on human DILI risk prediction
  • Noninvasive preclinical and clinical imaging of liver transporter function relevant to drug-induced liver injury
  • J. Gerry Kenna, John C. Waterton, Andreas Baudy, Aleksandra Galetin, Catherine D. G. Hines, Paul Hockings, Manishkumar Patel, Daniel Scotcher, Steven Sourbron, Sabina Ziemian, and Gunnar Schuetz
  • Shraddha Thakkar, Minjun Chen, Huixiao Hong, Zhichao Liu, Hong Fang, and Weida Tong
  • Physicochemical properties and structural alerts
  • Lilia Fisk, Nigel Greene, and Russ Naven
Control code
SPRP1029201431
Dimensions
unknown
Extent
1 online resource (xx, 667 pages)
File format
unknown
Form of item
online
Isbn
9781493976768
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color) ;
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • on1029201431
  • (OCoLC)1029201431

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