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The Resource Gene therapy protocols, edited by Jeffrey R. Morgan, (electronic book)

Gene therapy protocols, edited by Jeffrey R. Morgan, (electronic book)

Label
Gene therapy protocols
Title
Gene therapy protocols
Statement of responsibility
edited by Jeffrey R. Morgan
Contributor
Subject
Language
eng
Summary
Significant advances in gene transfer technology and the completion of sequencing the human genome offer much renewed hope that gene therapy will provide novel approaches to the treatment of inherited and acquired diseases. In this fully updated and revised 2nd edition of the warmly received Gene Therapy Protocols, leading experts from academic and industrial laboratories around the world detail their most effective viral and nonviral methods of gene transfer, as well as discuss their applications in different organ systems. The methods range from those in which new molecular conjugates show great promise for targeting targeting gene transfer and regulating transgene expression, to those used in such exciting applications as the delivery of therapeutic proteins, vaccination, and tissue engineering. In addition, there are completely revised methods based on retroviruses and adenoviruses, as well as new and promising methods based on lentiviruses and adeno-associated viruses. The quantitative aspects of gene therapy are strongly emphasized, and the book reflects the many significant recent improvements in gene transfer efficiency, gene regulation, and vector production. Up-to-date and highly practical, Gene Therapy Protocols, 2nd Edition, offers a rich compilation of the revolutionary advances that have recently occurred in gene transfer technology, with each article providing proven step-by-step laboratory procedures that enable successful therapeutic application. --
Member of
Assigning source
Provided by publisher
Cataloging source
N$T
Dewey number
616/.042
Illustrations
illustrations
Index
index present
LC call number
RB155.8
LC item number
.G465 2002
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
Morgan, Jeffrey Robert.
Series statement
Methods in molecular medicine
Series volume
69
http://library.link/vocab/subjectName
  • Gene therapy
  • HEALTH & FITNESS
  • MEDICAL
  • Gentherapie
  • Wetenschappelijke technieken
Label
Gene therapy protocols, edited by Jeffrey R. Morgan, (electronic book)
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Poly-l-lysine-based gene delivery systems. Synthesis, purification, and application / C.P. Lollo ... [et al.]-Immunizing potential of cytokine-transduced tumor cells / M.P. Colombo and M. Rodolfo-Targeted gene transfer to liver using protein-DNA complexes / C.H. Wu, C.M. Walton and G.Y. Wu-Receptor-directed molecular conjugates for gene transfer / A.G. Ziady and P.B. Davis-Particle-mediated gene transfer into dendritic cells : A novel strategy for the induction of immune responses against tumor antigens / T. Tuting and A. Albers-Cancer gene therapy with heat shock protein-65 gene / K.V. Lukacs and A. Nakakes-Gene transfer into muscle by electroporation in vivo / J. Miyazaki and H. Aihara-Recombinant vaccinia virus mva for generation and analysis of t cell responses against tumor associated antigens / I. Drexler ... [et al.]-Viral liposomes. Preparation and use / Y. Kaneda-Lpd nanoparticles--novel nonviral vector for efficient gene delivery / Y. Tan ... [et al.]-Selection of cytochrome p450 genes for use in prodrug activation-based cancer gene therapy / J.E. Hecht and D.J. Waxman-Solvoplex synthetic vector for intrapulmonary gene delivery. Preparation and use / K. Schughart and U.B. Rasmussen-Construction of p450-expressing tumor cell lines using retroviruses / J.E. Hecht, Y. Jounaidi and D.J. Waxman-7 in vitro methods for evaluation of p450-based anticancer gene therapy / D.H. JE and D.J. Waxman-Gene correction frequency by chimeric rna-DNA oligonucleotide using nuclear extracts / O.A. Igoucheva and K. Yoon-8 tumor models for evaluation of p450 gene therapy in vivo / J.E. Hecht, P. Schreiber Schwartz and D.J. Waxman-Regulated expression of plasmid-based gene therapies / R.V. Abruzzese ... [et al.]-9 intracellular single-chain antibodies for gene therapy / G. Bilbao ... [et al.]-Photochemical transfection. Light-induced, site-directed gene delivery / L. Prasmickaite, A. Hogset and K. Berg-Direct gene transfer and vaccination via skin transfection using a gene gun / C.F. Kuo, J.H. Wang and N.S. Yang-Preparation of pseudotyped retroviral vector / H. Yu-Combined adenoviral transfer of tumor suppressor and cell-cycle genes for tumor-cell apoptosis / K. Brand, V. Sandig and M. Strauss-Quantitative measurement of the concentration of active recombinant retrovirus / S.T. Andreadis and J.R. Morgan-Inhibition of cell growth by antisense oligonucleotides targeting the growth-related protein kinase c-raf / D. Fabbro ... [et al.]-Minigene-containing retroviral vectors using an alphavirus/retrovirus hybrid vector system. Production and use / J. Wahlfors and R.A. Morgan-Retrovirus-mediated gene transfer to human hematopoietic stem cells / W.P. Swaney ... [et al.]-Igf-1 antisense strategies for cancer treatment / Y.X. Pan and D.D. Anthony-Genetically modified skin substitutes. Preparation and use / K.E. Hamoen ... [et al.]-Anti-mdr1 ribozyme gene therapy / T. Ohnuma, H. Kobayashi and F.S. Wang-Bioartificial muscles in gene therapy / C. Powell ... [et al.]-Cytokine gene-modified cell-based cancer vaccines / R.T. Reilly ... [et al.]-Anti-c-erb1b2 ribozyme for gene therapy of breast cancer / T. Suzuki, M. Bessho and K.J. Scanlon-Hiv-based vectors. Preparation and use / A. Follenzi and L. Naldini-Anti-k-ras1 ribozyme adenoviral vector for gene therapy of non-small cell lung cancer / Y.A. Zhang, J. Nemunaitis and A.W. Tong-Green fluorescent protein retroviral vector : Generation of high-titer producer cells and virus supernatant / W. Uckert, L. Pedersen and W. Gunzburg-Packaging cell system for lentivirus vectors. Preparation and use / N. Srinivasakumar-Hsv-1 vectors for gene therapy of experimental cns tumors / U. Herrlinger ... [et al.]-Lentiviral vectors. Preparation and use / L.J. Chang and A.K. Zaiss-Intratumoral injection of naked DNA / J. Yang-Simian foamy virus vectors. Preparation and use / J. Park and A. Mergia-Cationic liposome gene transfer / K. Kay Son-In vivo particle-mediated gene transfer for cancer therapy / A.L. Rakhmilevich and N.S. Yang-Recombinant feline immunodeficiency virus vectors. Preparation and use / M.A. Curran and G.P. Nolan-Gene targeting to hepatomas (afp) / S. Tsuruta, A. Ido and S. Nagataki-Lentivirus vector based on simian immunodeficiency virus. Development and use / K. Uberla-Adenovirus-mediated targeted gene therapy for breast cancer and for purging hematopoietic stem-cell sources / L. Chen-Cytoplasmic rna vector derived from nontransmissible sendai virus. Production and use / A. Iida and M. Hasegawa-Preparation of helper-dependent adenoviral vectors / P. Ng, R.J. Parks and F.L. Graham-Chemotherapy-inducible vector for gene therapy of cancer / W. Walther ... [et al.]-Construction of first-generation adenoviral vectors / P. Ng and F.L. Graham-Oncolytic adenoviral vectors / R. Alemany and W.W. Zhang-Genetically modified clostridium for gene therapy of tumors / M.E. Fox ... [et al.]-Preparation of ovine adenovirus vectors / P. Loser ... [et al.]-Tumor-targeted salmonella: Strain development and expression of the hsv-tk effector gene / D. Bermudes, B. Low and J.M. Pawelek-Highly purified recombinant adeno-associated virus vectors. Preparation and quantitation / B. Schnepp and K.R. Clark-Ex vivo cytokine gene transfer in melanomas by using particle bombardment / D. Schadendorf-High-titer stocks of adeno-associated virus from replicating amplicons and herpes vectors / A.R. Mistry ... [et al.]-Intratumoral gene transfer of the hla-b7 gene into colon carcinoma metastases / E. Galanis and J. Rubin-Herpes simplex virus/adeno-associated virus hybrid vectors for gene transfer to neurons. Preparation and use / L.C. Costantini ... [et al.]-Hybrid cell vaccination in patients with metastatic melanoma / U. Trefzer ... [et al.]-Retroviral transfer of the herpes simplex virus-thymidine kinase (hsv-tk) gene for the treatment of cancer / R. Ramesh ... [et al.]-Development of replication-defective herpes simplex virus vectors / W.F. Goins ... [et al.]-Gene therapy for treatment of brain tumors (hsv-tkin vivo gene transfer) : A case study / F. Weber, F. Floeth and H. Bojar-Gene therapy of glioblastoma multiforme with a bicistronic retroviral vector expressing human il-2 and hsv-tk / G. Palu ... [et al.]-Intratumoral gene transfer of the cytosine deaminase gene for the treatment of breast cancer / H.S. Pandha and N.R. Lemoine-Adenovirus-mediated wild-type p53 gene transfer into head and neck cancers / G.L. Clayman, D.K. Frank and P.A. Bruso-Direct DNA injection (p53) into hcc tumors / R.R. Mitry and N.A. Habib-A phase ii trial of intratumoral injection with a selectively replicating adenovirus (onyx-015) in patients with recurrent, refractory squamous cell carcinoma of the head and neck / D.H. Kirn-C-myb antisense oligonucleotide therapeutics for hematologic malignancies / S. Luger-Ovarian cancer gene therapy with brca1-an overview / P.S. Obermiller and J.T. Holt-Methods for chemoprotection and chemosensitization : Mdr-1 for chemoprotection using retroviruses to modify hematopoietic cells and cytosine deaminase for chemosensitization using adenoviral vectors to modify epithelian neoplastic cells / S. Shrimdkandada ... [et al.]
Control code
SPR170924319
Dimensions
unknown
Edition
2nd ed.
Extent
1 online resource (xv, 520 p.)
File format
unknown
Form of item
online
Isbn
9780896038691
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
ill.
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
Label
Gene therapy protocols, edited by Jeffrey R. Morgan, (electronic book)
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Poly-l-lysine-based gene delivery systems. Synthesis, purification, and application / C.P. Lollo ... [et al.]-Immunizing potential of cytokine-transduced tumor cells / M.P. Colombo and M. Rodolfo-Targeted gene transfer to liver using protein-DNA complexes / C.H. Wu, C.M. Walton and G.Y. Wu-Receptor-directed molecular conjugates for gene transfer / A.G. Ziady and P.B. Davis-Particle-mediated gene transfer into dendritic cells : A novel strategy for the induction of immune responses against tumor antigens / T. Tuting and A. Albers-Cancer gene therapy with heat shock protein-65 gene / K.V. Lukacs and A. Nakakes-Gene transfer into muscle by electroporation in vivo / J. Miyazaki and H. Aihara-Recombinant vaccinia virus mva for generation and analysis of t cell responses against tumor associated antigens / I. Drexler ... [et al.]-Viral liposomes. Preparation and use / Y. Kaneda-Lpd nanoparticles--novel nonviral vector for efficient gene delivery / Y. Tan ... [et al.]-Selection of cytochrome p450 genes for use in prodrug activation-based cancer gene therapy / J.E. Hecht and D.J. Waxman-Solvoplex synthetic vector for intrapulmonary gene delivery. Preparation and use / K. Schughart and U.B. Rasmussen-Construction of p450-expressing tumor cell lines using retroviruses / J.E. Hecht, Y. Jounaidi and D.J. Waxman-7 in vitro methods for evaluation of p450-based anticancer gene therapy / D.H. JE and D.J. Waxman-Gene correction frequency by chimeric rna-DNA oligonucleotide using nuclear extracts / O.A. Igoucheva and K. Yoon-8 tumor models for evaluation of p450 gene therapy in vivo / J.E. Hecht, P. Schreiber Schwartz and D.J. Waxman-Regulated expression of plasmid-based gene therapies / R.V. Abruzzese ... [et al.]-9 intracellular single-chain antibodies for gene therapy / G. Bilbao ... [et al.]-Photochemical transfection. Light-induced, site-directed gene delivery / L. Prasmickaite, A. Hogset and K. Berg-Direct gene transfer and vaccination via skin transfection using a gene gun / C.F. Kuo, J.H. Wang and N.S. Yang-Preparation of pseudotyped retroviral vector / H. Yu-Combined adenoviral transfer of tumor suppressor and cell-cycle genes for tumor-cell apoptosis / K. Brand, V. Sandig and M. Strauss-Quantitative measurement of the concentration of active recombinant retrovirus / S.T. Andreadis and J.R. Morgan-Inhibition of cell growth by antisense oligonucleotides targeting the growth-related protein kinase c-raf / D. Fabbro ... [et al.]-Minigene-containing retroviral vectors using an alphavirus/retrovirus hybrid vector system. Production and use / J. Wahlfors and R.A. Morgan-Retrovirus-mediated gene transfer to human hematopoietic stem cells / W.P. Swaney ... [et al.]-Igf-1 antisense strategies for cancer treatment / Y.X. Pan and D.D. Anthony-Genetically modified skin substitutes. Preparation and use / K.E. Hamoen ... [et al.]-Anti-mdr1 ribozyme gene therapy / T. Ohnuma, H. Kobayashi and F.S. Wang-Bioartificial muscles in gene therapy / C. Powell ... [et al.]-Cytokine gene-modified cell-based cancer vaccines / R.T. Reilly ... [et al.]-Anti-c-erb1b2 ribozyme for gene therapy of breast cancer / T. Suzuki, M. Bessho and K.J. Scanlon-Hiv-based vectors. Preparation and use / A. Follenzi and L. Naldini-Anti-k-ras1 ribozyme adenoviral vector for gene therapy of non-small cell lung cancer / Y.A. Zhang, J. Nemunaitis and A.W. Tong-Green fluorescent protein retroviral vector : Generation of high-titer producer cells and virus supernatant / W. Uckert, L. Pedersen and W. Gunzburg-Packaging cell system for lentivirus vectors. Preparation and use / N. Srinivasakumar-Hsv-1 vectors for gene therapy of experimental cns tumors / U. Herrlinger ... [et al.]-Lentiviral vectors. Preparation and use / L.J. Chang and A.K. Zaiss-Intratumoral injection of naked DNA / J. Yang-Simian foamy virus vectors. Preparation and use / J. Park and A. Mergia-Cationic liposome gene transfer / K. Kay Son-In vivo particle-mediated gene transfer for cancer therapy / A.L. Rakhmilevich and N.S. Yang-Recombinant feline immunodeficiency virus vectors. Preparation and use / M.A. Curran and G.P. Nolan-Gene targeting to hepatomas (afp) / S. Tsuruta, A. Ido and S. Nagataki-Lentivirus vector based on simian immunodeficiency virus. Development and use / K. Uberla-Adenovirus-mediated targeted gene therapy for breast cancer and for purging hematopoietic stem-cell sources / L. Chen-Cytoplasmic rna vector derived from nontransmissible sendai virus. Production and use / A. Iida and M. Hasegawa-Preparation of helper-dependent adenoviral vectors / P. Ng, R.J. Parks and F.L. Graham-Chemotherapy-inducible vector for gene therapy of cancer / W. Walther ... [et al.]-Construction of first-generation adenoviral vectors / P. Ng and F.L. Graham-Oncolytic adenoviral vectors / R. Alemany and W.W. Zhang-Genetically modified clostridium for gene therapy of tumors / M.E. Fox ... [et al.]-Preparation of ovine adenovirus vectors / P. Loser ... [et al.]-Tumor-targeted salmonella: Strain development and expression of the hsv-tk effector gene / D. Bermudes, B. Low and J.M. Pawelek-Highly purified recombinant adeno-associated virus vectors. Preparation and quantitation / B. Schnepp and K.R. Clark-Ex vivo cytokine gene transfer in melanomas by using particle bombardment / D. Schadendorf-High-titer stocks of adeno-associated virus from replicating amplicons and herpes vectors / A.R. Mistry ... [et al.]-Intratumoral gene transfer of the hla-b7 gene into colon carcinoma metastases / E. Galanis and J. Rubin-Herpes simplex virus/adeno-associated virus hybrid vectors for gene transfer to neurons. Preparation and use / L.C. Costantini ... [et al.]-Hybrid cell vaccination in patients with metastatic melanoma / U. Trefzer ... [et al.]-Retroviral transfer of the herpes simplex virus-thymidine kinase (hsv-tk) gene for the treatment of cancer / R. Ramesh ... [et al.]-Development of replication-defective herpes simplex virus vectors / W.F. Goins ... [et al.]-Gene therapy for treatment of brain tumors (hsv-tkin vivo gene transfer) : A case study / F. Weber, F. Floeth and H. Bojar-Gene therapy of glioblastoma multiforme with a bicistronic retroviral vector expressing human il-2 and hsv-tk / G. Palu ... [et al.]-Intratumoral gene transfer of the cytosine deaminase gene for the treatment of breast cancer / H.S. Pandha and N.R. Lemoine-Adenovirus-mediated wild-type p53 gene transfer into head and neck cancers / G.L. Clayman, D.K. Frank and P.A. Bruso-Direct DNA injection (p53) into hcc tumors / R.R. Mitry and N.A. Habib-A phase ii trial of intratumoral injection with a selectively replicating adenovirus (onyx-015) in patients with recurrent, refractory squamous cell carcinoma of the head and neck / D.H. Kirn-C-myb antisense oligonucleotide therapeutics for hematologic malignancies / S. Luger-Ovarian cancer gene therapy with brca1-an overview / P.S. Obermiller and J.T. Holt-Methods for chemoprotection and chemosensitization : Mdr-1 for chemoprotection using retroviruses to modify hematopoietic cells and cytosine deaminase for chemosensitization using adenoviral vectors to modify epithelian neoplastic cells / S. Shrimdkandada ... [et al.]
Control code
SPR170924319
Dimensions
unknown
Edition
2nd ed.
Extent
1 online resource (xv, 520 p.)
File format
unknown
Form of item
online
Isbn
9780896038691
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
ill.
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote

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