Coverart for item
The Resource Gigaseal formation in patch clamping : with applications of nanotechnology, Majid Malboubi, Kyle Jiang, (electronic book)

Gigaseal formation in patch clamping : with applications of nanotechnology, Majid Malboubi, Kyle Jiang, (electronic book)

Label
Gigaseal formation in patch clamping : with applications of nanotechnology
Title
Gigaseal formation in patch clamping
Title remainder
with applications of nanotechnology
Statement of responsibility
Majid Malboubi, Kyle Jiang
Creator
Contributor
Subject
Language
eng
Summary
This book presents an investigation of gigaseal formation using micro/nanotechnology. The aims of the book are twofold. First, it explains the mechanisms of gigaseal formation using the latest discoveries. Second, it provides practical techniques for frequent formation of high resistance seals. The formation of a high-resistance electrical seal, also known as a gigaseal, between a cell membrane and a glass micropipette tip is essential in patch-clamp experiments. Even though four decades have passed since the introduction of the patch-clamping technique by Neher and Sakmann, gigaseal formation remains an obstacle in developing the high-throughput ion channel screening systems required by the pharmaceutical industry. Here the authors share their latest methods for achieving gigaseal formation and describe techniques that are highly desirable at both research and industrial levels. Nanotechnology has been found to be a powerful tool for studying and modifying glass micropipettes and in tackling the problem of gigaseal formation
Member of
Cataloging source
N$T
http://library.link/vocab/creatorName
Malboubi, Majid
Dewey number
572/.437
Index
no index present
LC call number
QH517
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
Jiang, Kyle
Series statement
Springer briefs in applied sciences and technology
http://library.link/vocab/subjectName
  • Patch-clamp techniques (Electrophysiology)
  • Nanotechnology
Label
Gigaseal formation in patch clamping : with applications of nanotechnology, Majid Malboubi, Kyle Jiang, (electronic book)
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
  • Introduction
  • Development of patch clamping
  • Gigaseal formation
  • Effect of roughness on gigaseal formation
  • Effect of hydrophilicIty on gigaseal formation
  • Effect of tip size on gigaseal formation
  • Study of glass micropipettes from tip formation to characterization
  • References
Control code
SPR856013531
Dimensions
unknown
Extent
1 online resource.
File format
unknown
Form of item
online
Isbn
9783642391286
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
c
Quality assurance targets
not applicable
Reformatting quality
unknown
Reproduction note
Electronic resource.
Sound
unknown sound
Specific material designation
remote
Label
Gigaseal formation in patch clamping : with applications of nanotechnology, Majid Malboubi, Kyle Jiang, (electronic book)
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
  • Introduction
  • Development of patch clamping
  • Gigaseal formation
  • Effect of roughness on gigaseal formation
  • Effect of hydrophilicIty on gigaseal formation
  • Effect of tip size on gigaseal formation
  • Study of glass micropipettes from tip formation to characterization
  • References
Control code
SPR856013531
Dimensions
unknown
Extent
1 online resource.
File format
unknown
Form of item
online
Isbn
9783642391286
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
c
Quality assurance targets
not applicable
Reformatting quality
unknown
Reproduction note
Electronic resource.
Sound
unknown sound
Specific material designation
remote

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