Coverart for item
The Resource Imaginal discs : the genetic and cellular logic of pattern formation, Lewis I. Held, Jr

Imaginal discs : the genetic and cellular logic of pattern formation, Lewis I. Held, Jr

Label
Imaginal discs : the genetic and cellular logic of pattern formation
Title
Imaginal discs
Title remainder
the genetic and cellular logic of pattern formation
Statement of responsibility
Lewis I. Held, Jr
Creator
Contributor
Subject
Language
eng
Summary
Many of the 14,000 genes of Drosophila are involved in the development of imaginal discs. These hollow sacs of cells make adult structures during metamorphosis, and their study is crucial to comprehending how a larva becomes a fully-functioning fly. This book examines the genetic circuitry of the well-known 'fruit fly', tackling questions of cell assemblage and pattern formation, of the hows and the whys behind the development of the fly. After an initial examination of the proximity versus pedigree imperatives, the book delves into bristle pattern formation and disc development, with entire chapters devoted to the leg, wing, and eye. Extensive appendices include a glossary of protein domains, catalogues of well-studied genes, and an outline of signaling pathways. More than 30 wiring diagrams among over 60 detailed schematics clarify the text. No student or practising scientist engaged in the study of Drosophila genetics should be without this comprehensive reference
Member of
Cataloging source
UkCbUP
http://library.link/vocab/creatorDate
1951-
http://library.link/vocab/creatorName
Held, Lewis I.
Dewey number
576.5
Index
index present
LC call number
QH470.D7
LC item number
H45 2002
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
Cambridge University Press.
Series statement
Developmental and cell biology series
Series volume
39
http://library.link/vocab/subjectName
  • Drosophila melanogaster
  • Drosophila melanogaster
  • Drosophila melanogaster
  • Cellular signal transduction
  • Cell interaction
Label
Imaginal discs : the genetic and cellular logic of pattern formation, Lewis I. Held, Jr
Instantiates
Publication
Note
Title from publisher's bibliographic system (viewed on 05 Oct 2015)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Delta needs to activate Notch, but not as a signal per se.
  • Amnesic cells can use sequential gating to simulate a binary code.
  • Notch must go to the nucleus to function.
  • E(spl)-C genes are Su(H) targets but play no role in the SOP lineage.
  • The transcription factor Tramtrack implements some cell identities.
  • Hairless titrated Su(H).
  • Several other genes help determine the 5 cell fates.
  • Pox neuro and Cut specify bristle type.
  • Bract cells are induced by bristle cells
  • Ch. 1.
  • Cell Lineage vs. Intercellular Signaling.
  • Discs are not clones.
  • No part of a disc is a clone, except claws and tiny sense organs.
  • Cells belong to lineage "compartments"
  • Ch. 2.
  • The Bristle.
  • Numb segregates asymmetrically and dictates bristle cell fates.
Control code
CR9780511529733
Extent
1 online resource (xv, 460 pages)
Form of item
online
Isbn
9780521018357
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
digital, PDF file(s).
Specific material designation
remote
Label
Imaginal discs : the genetic and cellular logic of pattern formation, Lewis I. Held, Jr
Publication
Note
Title from publisher's bibliographic system (viewed on 05 Oct 2015)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Delta needs to activate Notch, but not as a signal per se.
  • Amnesic cells can use sequential gating to simulate a binary code.
  • Notch must go to the nucleus to function.
  • E(spl)-C genes are Su(H) targets but play no role in the SOP lineage.
  • The transcription factor Tramtrack implements some cell identities.
  • Hairless titrated Su(H).
  • Several other genes help determine the 5 cell fates.
  • Pox neuro and Cut specify bristle type.
  • Bract cells are induced by bristle cells
  • Ch. 1.
  • Cell Lineage vs. Intercellular Signaling.
  • Discs are not clones.
  • No part of a disc is a clone, except claws and tiny sense organs.
  • Cells belong to lineage "compartments"
  • Ch. 2.
  • The Bristle.
  • Numb segregates asymmetrically and dictates bristle cell fates.
Control code
CR9780511529733
Extent
1 online resource (xv, 460 pages)
Form of item
online
Isbn
9780521018357
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
digital, PDF file(s).
Specific material designation
remote

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