Coverart for item
The Resource Neural control of renal function, Ulla C. Kopp, (electronic book)

Neural control of renal function, Ulla C. Kopp, (electronic book)

Label
Neural control of renal function
Title
Neural control of renal function
Statement of responsibility
Ulla C. Kopp
Creator
Subject
Language
eng
Summary
The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of [beta]1-adrenoceptors and increase renin secretion rate by activation of [beta]1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Activation of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension
Member of
Cataloging source
CaBNVSL
http://library.link/vocab/creatorName
Kopp, Ulla.
Dewey number
617.4610592
Illustrations
illustrations
Index
no index present
LC call number
RD575
LC item number
.K665 2011
Literary form
non fiction
Nature of contents
  • dictionaries
  • abstracts summaries
  • bibliography
Series statement
Colloquium series on integrated systems physiology, from molecule to function
Series volume
22
http://library.link/vocab/subjectName
Kidneys
Target audience
  • adult
  • specialized
Label
Neural control of renal function, Ulla C. Kopp, (electronic book)
Instantiates
Publication
Bibliography note
Includes bibliographical references (p. 65-84)
Color
multicolored
Contents
  • Part I. Efferent renal sympathetic nerves -- 1. Introduction --
  • 2. Neuroanatomy -- 2.1 Neural pathways -- 2.2 Intrarenal distribution of efferent renal sympathetic nerves -- 2.3 Characteristics of the efferent renal sympathetic nerve signals -- 2.4 Neurotransmitters -- 2.5 Adrenoceptors -- 2.6 Angiotensin II, nitric oxide, and reactive oxygen species --
  • 3. Neural control of renal hemodynamics -- 3.1 Measurements of renal blood flow -- 3.2 Renal denervation -- 3.3 Increases in renal sympathetic nerve activity -- 3.4 Adrenoceptors --
  • 4. Neural control of renal tubular function -- 4.1 Renal denervation -- 4.2 Increases in renal sympathetic nerve activity -- 4.2.1 Direct activation of the renal nerves -- 4.2.2 Reflex-mediated increases and decreases in the activation of the renal nerves -- 4.3 Adrenoceptors --
  • 5. Neural control of renin secretion rate -- 5.1 Increases in efferent renal sympathetic nerve activity -- 5.2 Interaction between neural and non-neural mechanisms for renin secretion -- 5.3 Adrenoceptor --
  • Part II. Afferent renal sensory nerves -- 6. Introduction --
  • 7. Neuroanatomy -- 7.1 Kidney -- 7.2 Projection to the central nervous system --
  • 8. Renorenal reflexes -- 8.1 Activation of afferent renal sensory nerves by physiological stimuli -- 8.2 Selective afferent renal denervation-dorsal rhizotomy -- 8.3 Interaction between efferent and afferent renal nerve activity --
  • 9. Mechanisms involved in the activation of afferent renal sensory nerves -- 9.1 Substance P -- 9.2 Mechanisms contributing to the release of substance P from renal pelvic sensory nerves -- 9.2.1 PGE2 -- 9.2.2 Angiotensin II -- 9.2.3 Endothelin -- Part III. Pathophysiological states --
  • 10. Efferent renal sympathetic nerves -- 10.1 Hypertension -- 10.2 Heart failure -- 10.3 Cirrhosis and nephrotic syndrome --
  • 11. Afferent renal sensory nerves --
  • 12. Conclusions -- References -- Author biography
Control code
201106ISP022
Dimensions
unknown
Extent
1 electronic text (x, 85 p.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615042319
Other physical details
ill., digital file
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader
Label
Neural control of renal function, Ulla C. Kopp, (electronic book)
Publication
Bibliography note
Includes bibliographical references (p. 65-84)
Color
multicolored
Contents
  • Part I. Efferent renal sympathetic nerves -- 1. Introduction --
  • 2. Neuroanatomy -- 2.1 Neural pathways -- 2.2 Intrarenal distribution of efferent renal sympathetic nerves -- 2.3 Characteristics of the efferent renal sympathetic nerve signals -- 2.4 Neurotransmitters -- 2.5 Adrenoceptors -- 2.6 Angiotensin II, nitric oxide, and reactive oxygen species --
  • 3. Neural control of renal hemodynamics -- 3.1 Measurements of renal blood flow -- 3.2 Renal denervation -- 3.3 Increases in renal sympathetic nerve activity -- 3.4 Adrenoceptors --
  • 4. Neural control of renal tubular function -- 4.1 Renal denervation -- 4.2 Increases in renal sympathetic nerve activity -- 4.2.1 Direct activation of the renal nerves -- 4.2.2 Reflex-mediated increases and decreases in the activation of the renal nerves -- 4.3 Adrenoceptors --
  • 5. Neural control of renin secretion rate -- 5.1 Increases in efferent renal sympathetic nerve activity -- 5.2 Interaction between neural and non-neural mechanisms for renin secretion -- 5.3 Adrenoceptor --
  • Part II. Afferent renal sensory nerves -- 6. Introduction --
  • 7. Neuroanatomy -- 7.1 Kidney -- 7.2 Projection to the central nervous system --
  • 8. Renorenal reflexes -- 8.1 Activation of afferent renal sensory nerves by physiological stimuli -- 8.2 Selective afferent renal denervation-dorsal rhizotomy -- 8.3 Interaction between efferent and afferent renal nerve activity --
  • 9. Mechanisms involved in the activation of afferent renal sensory nerves -- 9.1 Substance P -- 9.2 Mechanisms contributing to the release of substance P from renal pelvic sensory nerves -- 9.2.1 PGE2 -- 9.2.2 Angiotensin II -- 9.2.3 Endothelin -- Part III. Pathophysiological states --
  • 10. Efferent renal sympathetic nerves -- 10.1 Hypertension -- 10.2 Heart failure -- 10.3 Cirrhosis and nephrotic syndrome --
  • 11. Afferent renal sensory nerves --
  • 12. Conclusions -- References -- Author biography
Control code
201106ISP022
Dimensions
unknown
Extent
1 electronic text (x, 85 p.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615042319
Other physical details
ill., digital file
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader

Library Locations

Processing Feedback ...