Coverart for item
The Resource Nuclear architecture and dynamics, edited by Christophe Lavelle, Jean-Marc Victor, (electronic book)

Nuclear architecture and dynamics, edited by Christophe Lavelle, Jean-Marc Victor, (electronic book)

Label
Nuclear architecture and dynamics
Title
Nuclear architecture and dynamics
Statement of responsibility
edited by Christophe Lavelle, Jean-Marc Victor
Contributor
Editor
Subject
Language
eng
Summary
Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field. The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines
Member of
Cataloging source
YDX
Dewey number
574.8732
http://bibfra.me/vocab/relation/ditor
DeQ0ZQaHvQo
Illustrations
illustrations
Index
index present
LC call number
QH595
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Lavelle, Christophe
  • Victor, Jean-Marc
Series statement
Translational epigenetics series
Series volume
2
http://library.link/vocab/subjectName
Cell nuclei
Label
Nuclear architecture and dynamics, edited by Christophe Lavelle, Jean-Marc Victor, (electronic book)
Instantiates
Publication
Note
Includes index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • ""Front Cover""; ""Nuclear Architecture and Dynamics""; ""Copyright Page""; ""Contents""; ""List of Contributors""; ""Preface""; ""I. Chromatin Organization and Dynamics""; ""1 DNA Mechanics""; ""1.1 Basic Properties of DNA""; ""1.1.1 The DNA Double Helix""; ""1.1.2 Physical Properties of the DNA Double Helix""; ""1.1.2.1 Length""; ""1.1.2.2 Electrical Charge""; ""1.1.2.3 Bending Stiffness""; ""1.1.2.4 Helical Structure and Twisting Stiffness""; ""1.1.3 Physical Scales Relevant to DNA""; ""1.1.3.1 Length""; ""1.1.3.2 Concentration""; ""1.1.3.3 Energy""; ""1.1.3.4 Force""; ""1.1.3.5 Time""
  • ""1.2 The Double Helix Is a Semiflexible Polymer""""1.2.1 Bending DNA Into Small Loops""; ""1.2.1.1 Permanent Sequence-Driven Bends""; ""1.2.2 Statistical Mechanics of the Semiflexible Polymer""; ""1.2.2.1 Stretching the Semiflexible Polymer by Small Forces (<kBT/A)""; ""1.2.2.2 External Force on a Polymer""; ""1.2.2.3 Higher-Force Behavior of the Semiflexible Polymer and DNA""; ""1.2.2.4 High-Force Elastic Deformation of the Double Helix""; ""1.2.2.5 Effective Youngâ#x80;#x99;s Modulus of the Double Helix""; ""1.3 Double-Helix Topology and Twisting Stiffness""; ""1.3.1 Linking Number of Two Curves""
  • ""1.3.2 Internal Double-Helix Linking Number Lk""""1.3.3 DNA Twist Stiffness""; ""1.3.4 Decomposition of Double-Helix Lk Into Twist Tw and Writhe Wr""; ""1.3.5 DNA Supercoiling""; ""1.3.6 Twisting Stretched DNA""; ""1.3.7 Coexistence of Supercoiled and Twisted Stretched DNA""; ""1.4 Beyond the Decoupled Harmonic Model of Double-Helix Elasticity""; ""1.4.1 Elastic Coupling of DNA Bending, Twisting, and Stretching""; ""1.4.1.1 Twistâ#x80;#x93;Stretch Coupling""; ""1.4.1.2 Twistâ#x80;#x93;Bend Coupling""; ""1.4.1.3 Strain Gradient Coupling""; ""1.5 Severe Deformations of the Double Helix""; ""1.5.1 Unzipping""
  • ""1.5.2 Overstretching""""1.5.3 Unwinding""; ""1.5.4 Sharp Bending of the Double Helix""; ""1.6 Overview of DNAâ#x80;#x93;Protein Interactions""; ""1.6.1 Classical Two-State Kinetic/Thermodynamic Model of Protein Binding a DNA Site""; ""1.6.2 Salt-Concentration-Dependence of Proteins Binding to DNA""; ""1.6.3 Force Effect on Proteinâ#x80;#x93;DNA Binding""; ""References""; ""2 The Role of Nucleosome Positioning in Genome Function and Evolution""; ""2.1 Introduction""; ""2.2 A Sequence-Dependent Physical Model of Nucleosome Occupancy""; ""2.2.1 Intrinsic Nucleosome Formation Energy""
  • ""2.2.2 Grand Canonical Modeling of Nucleosome Occupancy Landscape""""2.2.2.1 Intrinsic Nucleosome Density Profile""; ""2.2.2.2 Intrinsic Nucleosome Occupancy Profile and Model Parameters""; ""2.3 Comparing In Vivo and In Vitro Primary Structures of Chromatin""; ""2.3.1 Nucleosome Ordering Near NIEBs: Organizing via Excluding?""; ""2.3.2 Modeling of In Vitro Nucleosome Occupancy Data""; ""2.3.3 Modeling of In Vivo Nucleosome Occupancy Data""; ""2.3.4 Intrinsic NIEBs in Eukaryotic Genomes""; ""2.3.4.1 Algorithm to Predict NIEBs""
Dimensions
unknown
Extent
1 online resource
Form of item
online
Isbn
9780128035030
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
Specific material designation
remote
System control number
  • (OCoLC)1006617043
  • on1006617043
Label
Nuclear architecture and dynamics, edited by Christophe Lavelle, Jean-Marc Victor, (electronic book)
Publication
Note
Includes index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • ""Front Cover""; ""Nuclear Architecture and Dynamics""; ""Copyright Page""; ""Contents""; ""List of Contributors""; ""Preface""; ""I. Chromatin Organization and Dynamics""; ""1 DNA Mechanics""; ""1.1 Basic Properties of DNA""; ""1.1.1 The DNA Double Helix""; ""1.1.2 Physical Properties of the DNA Double Helix""; ""1.1.2.1 Length""; ""1.1.2.2 Electrical Charge""; ""1.1.2.3 Bending Stiffness""; ""1.1.2.4 Helical Structure and Twisting Stiffness""; ""1.1.3 Physical Scales Relevant to DNA""; ""1.1.3.1 Length""; ""1.1.3.2 Concentration""; ""1.1.3.3 Energy""; ""1.1.3.4 Force""; ""1.1.3.5 Time""
  • ""1.2 The Double Helix Is a Semiflexible Polymer""""1.2.1 Bending DNA Into Small Loops""; ""1.2.1.1 Permanent Sequence-Driven Bends""; ""1.2.2 Statistical Mechanics of the Semiflexible Polymer""; ""1.2.2.1 Stretching the Semiflexible Polymer by Small Forces (<kBT/A)""; ""1.2.2.2 External Force on a Polymer""; ""1.2.2.3 Higher-Force Behavior of the Semiflexible Polymer and DNA""; ""1.2.2.4 High-Force Elastic Deformation of the Double Helix""; ""1.2.2.5 Effective Youngâ#x80;#x99;s Modulus of the Double Helix""; ""1.3 Double-Helix Topology and Twisting Stiffness""; ""1.3.1 Linking Number of Two Curves""
  • ""1.3.2 Internal Double-Helix Linking Number Lk""""1.3.3 DNA Twist Stiffness""; ""1.3.4 Decomposition of Double-Helix Lk Into Twist Tw and Writhe Wr""; ""1.3.5 DNA Supercoiling""; ""1.3.6 Twisting Stretched DNA""; ""1.3.7 Coexistence of Supercoiled and Twisted Stretched DNA""; ""1.4 Beyond the Decoupled Harmonic Model of Double-Helix Elasticity""; ""1.4.1 Elastic Coupling of DNA Bending, Twisting, and Stretching""; ""1.4.1.1 Twistâ#x80;#x93;Stretch Coupling""; ""1.4.1.2 Twistâ#x80;#x93;Bend Coupling""; ""1.4.1.3 Strain Gradient Coupling""; ""1.5 Severe Deformations of the Double Helix""; ""1.5.1 Unzipping""
  • ""1.5.2 Overstretching""""1.5.3 Unwinding""; ""1.5.4 Sharp Bending of the Double Helix""; ""1.6 Overview of DNAâ#x80;#x93;Protein Interactions""; ""1.6.1 Classical Two-State Kinetic/Thermodynamic Model of Protein Binding a DNA Site""; ""1.6.2 Salt-Concentration-Dependence of Proteins Binding to DNA""; ""1.6.3 Force Effect on Proteinâ#x80;#x93;DNA Binding""; ""References""; ""2 The Role of Nucleosome Positioning in Genome Function and Evolution""; ""2.1 Introduction""; ""2.2 A Sequence-Dependent Physical Model of Nucleosome Occupancy""; ""2.2.1 Intrinsic Nucleosome Formation Energy""
  • ""2.2.2 Grand Canonical Modeling of Nucleosome Occupancy Landscape""""2.2.2.1 Intrinsic Nucleosome Density Profile""; ""2.2.2.2 Intrinsic Nucleosome Occupancy Profile and Model Parameters""; ""2.3 Comparing In Vivo and In Vitro Primary Structures of Chromatin""; ""2.3.1 Nucleosome Ordering Near NIEBs: Organizing via Excluding?""; ""2.3.2 Modeling of In Vitro Nucleosome Occupancy Data""; ""2.3.3 Modeling of In Vivo Nucleosome Occupancy Data""; ""2.3.4 Intrinsic NIEBs in Eukaryotic Genomes""; ""2.3.4.1 Algorithm to Predict NIEBs""
Dimensions
unknown
Extent
1 online resource
Form of item
online
Isbn
9780128035030
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
Specific material designation
remote
System control number
  • (OCoLC)1006617043
  • on1006617043

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