Coverart for item
The Resource Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches, Gustavo Duque, Douglas P. Kiel, editors, (electronic book)

Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches, Gustavo Duque, Douglas P. Kiel, editors, (electronic book)

Label
Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches
Title
Osteoporosis in older persons
Title remainder
advances in pathophysiology and therapeutic approaches
Statement of responsibility
Gustavo Duque, Douglas P. Kiel, editors
Contributor
Subject
Language
eng
Summary
This second edition brings together the latest information about the pathophysiology and new therapeutic alternatives for osteoporosis of advanced age. Written by highly recognised clinicians and basic scientists in the field of aging bone research, this book includes aspects of muscle and bone interaction focusing on the impact of age-related muscle loss (sarcopenia) on the pathogenesis of falls and fractures in older persons. Osteoporosis in Older Persons- Advances in Pathophysiology and Therapeutic Approach, Second Edition, aids the reader in understanding the mechanisms of senile osteoporosis with a practical approach to the treatment of its consequences. It is the perfect reference guide for geriatricians, gerontologists and bone biologists, as well as medical trainees.
Cataloging source
EBLCP
Dewey number
  • 616.7/16
  • 610
Index
no index present
LC call number
RC931.O73
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Duque, Gustavo
  • Kiel, Douglas P
http://library.link/vocab/subjectName
Osteoporosis
Label
Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches, Gustavo Duque, Douglas P. Kiel, editors, (electronic book)
Instantiates
Publication
Note
Implications for Screening
Antecedent source
unknown
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Acknowledgements; Foreword; Preface; Contents; Contributors; 1: Biology of Bone; Overview; Bone Growth and Development; Bone Cell Differentiation; Osteoprogenitors, Osteoblasts, and Osteocytes; Regulators of Osteoblastic Cell Differentiation and Function; Wnt Signaling Molecules; Parathyroid Hormone; Vitamin D3; Estrogen; Bone Morphogenetic Proteins; Growth Hormone/Insulin-Like Growth Factor; Leptin/[beta] Adrenergic Receptors; Glucocorticoids; Thyroid Hormone; MicroRNAs; Monocytes/Macrophages and Osteoclastogenesis; Modulators of Osteoclastic Cell Differentiation and Function
  • Bone Turnover Measurement of Bone Turnover; Bone Formation Markers; Bone Resorption Markers; Bone Turnover and Aging; Role of Bone and Bone Cells in Stem Cell Biology; References; 2: Aging and Bone; Introduction; Aging: A Definition; Contribution of Telomere Shortening to Age-Related Osteoblast Dysfunction; Other Aspects of Cellular Senescence; Aging and Bone Physiology; Skeletal Stem Cell (Also Known as Bone Marrow Stromal or Mesenchymal Stem Cells) (BMSC); The Inverse Relationship Between Adipocytes and Osteoblasts
  • Biochemical Signaling Pathways, Genetic and Pharmaceutical Targets in Aging Why Fat?; Which Fat?; What Makes It Bone vs. Fat?; Apoptosis and the Aging Bone; References; 3: Calciotropic Hormones; Calcium; Vitamin D; Parathyroid Hormone; Calcitonin; Summary/Conclusion; References; 4: The Muscle-Bone Connection; Mechanical Coupling of Bones and Muscles; Beyond Mechanical Coupling: Bone-Muscle Developmental and Genetic Coupling; Genome Wide Association Studies (GWAS); Disease Conditions with Multiple Tissue Effects; The Unique Case of Fracture Healing
  • Bones and Muscles as Endocrine Organs Bone as an Endocrine Organ; Muscle as an Endocrine Organ; Interplay Between Bones and Muscles as Endocrine Organs; Musculoskeletal Diseases: The Special Cases of Osteoporosis and Sarcopenia; Osteoporosis; Sarcopenia; The Role of Cartilage, Ligaments, and Tendons in Bone-Muscle Crosstalk; Crosstalk in MSK Development; Bone-Cartilage Crosstalk; Tendon-Muscle Crosstalk; Concluding Remarks and Future Directions; References; 5: Sex Steroids and Aging Bone; Introduction; Methodologic Issues; Sex Steroids and Age
  • Sex Steroids and Bone Mineral Density (BMD) Women; Men; Sex Steroids, Volumetric BMD and Skeletal Structure; Sex Steroids and Fractures; Women; Men; Summary; References; 6: Animal Models for Aging Bone; Introduction; Normally Aged Animal Models; Genetic Manipulation and Accelerated Aging; Osteopenia Caused by Decrease in Bone Formation; The Aging Phenotype and Defects in Mineral Metabolism; What Mouse Models Teach; References; 7: Osteoporosis as a Geriatric Syndrome; Introduction; What is a Geriatric Syndrome?; The Case for Osteoporotic Fractures as a Geriatric Syndrome
Control code
SPR953662123
Dimensions
unknown
Edition
2nd ed.
Extent
1 online resource (299 p.)
File format
unknown
Form of item
online
Isbn
9783319259765
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-319-25976-5
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
Label
Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches, Gustavo Duque, Douglas P. Kiel, editors, (electronic book)
Publication
Note
Implications for Screening
Antecedent source
unknown
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Acknowledgements; Foreword; Preface; Contents; Contributors; 1: Biology of Bone; Overview; Bone Growth and Development; Bone Cell Differentiation; Osteoprogenitors, Osteoblasts, and Osteocytes; Regulators of Osteoblastic Cell Differentiation and Function; Wnt Signaling Molecules; Parathyroid Hormone; Vitamin D3; Estrogen; Bone Morphogenetic Proteins; Growth Hormone/Insulin-Like Growth Factor; Leptin/[beta] Adrenergic Receptors; Glucocorticoids; Thyroid Hormone; MicroRNAs; Monocytes/Macrophages and Osteoclastogenesis; Modulators of Osteoclastic Cell Differentiation and Function
  • Bone Turnover Measurement of Bone Turnover; Bone Formation Markers; Bone Resorption Markers; Bone Turnover and Aging; Role of Bone and Bone Cells in Stem Cell Biology; References; 2: Aging and Bone; Introduction; Aging: A Definition; Contribution of Telomere Shortening to Age-Related Osteoblast Dysfunction; Other Aspects of Cellular Senescence; Aging and Bone Physiology; Skeletal Stem Cell (Also Known as Bone Marrow Stromal or Mesenchymal Stem Cells) (BMSC); The Inverse Relationship Between Adipocytes and Osteoblasts
  • Biochemical Signaling Pathways, Genetic and Pharmaceutical Targets in Aging Why Fat?; Which Fat?; What Makes It Bone vs. Fat?; Apoptosis and the Aging Bone; References; 3: Calciotropic Hormones; Calcium; Vitamin D; Parathyroid Hormone; Calcitonin; Summary/Conclusion; References; 4: The Muscle-Bone Connection; Mechanical Coupling of Bones and Muscles; Beyond Mechanical Coupling: Bone-Muscle Developmental and Genetic Coupling; Genome Wide Association Studies (GWAS); Disease Conditions with Multiple Tissue Effects; The Unique Case of Fracture Healing
  • Bones and Muscles as Endocrine Organs Bone as an Endocrine Organ; Muscle as an Endocrine Organ; Interplay Between Bones and Muscles as Endocrine Organs; Musculoskeletal Diseases: The Special Cases of Osteoporosis and Sarcopenia; Osteoporosis; Sarcopenia; The Role of Cartilage, Ligaments, and Tendons in Bone-Muscle Crosstalk; Crosstalk in MSK Development; Bone-Cartilage Crosstalk; Tendon-Muscle Crosstalk; Concluding Remarks and Future Directions; References; 5: Sex Steroids and Aging Bone; Introduction; Methodologic Issues; Sex Steroids and Age
  • Sex Steroids and Bone Mineral Density (BMD) Women; Men; Sex Steroids, Volumetric BMD and Skeletal Structure; Sex Steroids and Fractures; Women; Men; Summary; References; 6: Animal Models for Aging Bone; Introduction; Normally Aged Animal Models; Genetic Manipulation and Accelerated Aging; Osteopenia Caused by Decrease in Bone Formation; The Aging Phenotype and Defects in Mineral Metabolism; What Mouse Models Teach; References; 7: Osteoporosis as a Geriatric Syndrome; Introduction; What is a Geriatric Syndrome?; The Case for Osteoporotic Fractures as a Geriatric Syndrome
Control code
SPR953662123
Dimensions
unknown
Edition
2nd ed.
Extent
1 online resource (299 p.)
File format
unknown
Form of item
online
Isbn
9783319259765
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-319-25976-5
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote

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