The Resource Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches, Gustavo Duque, Douglas P. Kiel, editors, (electronic book)
Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches, Gustavo Duque, Douglas P. Kiel, editors, (electronic book)
Resource Information
The item Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches, Gustavo Duque, Douglas P. Kiel, editors, (electronic book) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Liverpool.This item is available to borrow from 1 library branch.
Resource Information
The item Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches, Gustavo Duque, Douglas P. Kiel, editors, (electronic book) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Liverpool.
This item is available to borrow from 1 library branch.
- Summary
- This second edition brings together the latest information about the pathophysiology and new therapeutic alternatives for osteoporosis of advanced age. Written by highly recognised clinicians and basic scientists in the field of aging bone research, this book includes aspects of muscle and bone interaction focusing on the impact of age-related muscle loss (sarcopenia) on the pathogenesis of falls and fractures in older persons. Osteoporosis in Older Persons- Advances in Pathophysiology and Therapeutic Approach, Second Edition, aids the reader in understanding the mechanisms of senile osteoporosis with a practical approach to the treatment of its consequences. It is the perfect reference guide for geriatricians, gerontologists and bone biologists, as well as medical trainees.
- Language
- eng
- Edition
- 2nd ed.
- Extent
- 1 online resource (299 p.)
- Note
- Implications for Screening
- Contents
-
- Acknowledgements; Foreword; Preface; Contents; Contributors; 1: Biology of Bone; Overview; Bone Growth and Development; Bone Cell Differentiation; Osteoprogenitors, Osteoblasts, and Osteocytes; Regulators of Osteoblastic Cell Differentiation and Function; Wnt Signaling Molecules; Parathyroid Hormone; Vitamin D3; Estrogen; Bone Morphogenetic Proteins; Growth Hormone/Insulin-Like Growth Factor; Leptin/[beta] Adrenergic Receptors; Glucocorticoids; Thyroid Hormone; MicroRNAs; Monocytes/Macrophages and Osteoclastogenesis; Modulators of Osteoclastic Cell Differentiation and Function
- Bone Turnover Measurement of Bone Turnover; Bone Formation Markers; Bone Resorption Markers; Bone Turnover and Aging; Role of Bone and Bone Cells in Stem Cell Biology; References; 2: Aging and Bone; Introduction; Aging: A Definition; Contribution of Telomere Shortening to Age-Related Osteoblast Dysfunction; Other Aspects of Cellular Senescence; Aging and Bone Physiology; Skeletal Stem Cell (Also Known as Bone Marrow Stromal or Mesenchymal Stem Cells) (BMSC); The Inverse Relationship Between Adipocytes and Osteoblasts
- Biochemical Signaling Pathways, Genetic and Pharmaceutical Targets in Aging Why Fat?; Which Fat?; What Makes It Bone vs. Fat?; Apoptosis and the Aging Bone; References; 3: Calciotropic Hormones; Calcium; Vitamin D; Parathyroid Hormone; Calcitonin; Summary/Conclusion; References; 4: The Muscle-Bone Connection; Mechanical Coupling of Bones and Muscles; Beyond Mechanical Coupling: Bone-Muscle Developmental and Genetic Coupling; Genome Wide Association Studies (GWAS); Disease Conditions with Multiple Tissue Effects; The Unique Case of Fracture Healing
- Bones and Muscles as Endocrine Organs Bone as an Endocrine Organ; Muscle as an Endocrine Organ; Interplay Between Bones and Muscles as Endocrine Organs; Musculoskeletal Diseases: The Special Cases of Osteoporosis and Sarcopenia; Osteoporosis; Sarcopenia; The Role of Cartilage, Ligaments, and Tendons in Bone-Muscle Crosstalk; Crosstalk in MSK Development; Bone-Cartilage Crosstalk; Tendon-Muscle Crosstalk; Concluding Remarks and Future Directions; References; 5: Sex Steroids and Aging Bone; Introduction; Methodologic Issues; Sex Steroids and Age
- Sex Steroids and Bone Mineral Density (BMD) Women; Men; Sex Steroids, Volumetric BMD and Skeletal Structure; Sex Steroids and Fractures; Women; Men; Summary; References; 6: Animal Models for Aging Bone; Introduction; Normally Aged Animal Models; Genetic Manipulation and Accelerated Aging; Osteopenia Caused by Decrease in Bone Formation; The Aging Phenotype and Defects in Mineral Metabolism; What Mouse Models Teach; References; 7: Osteoporosis as a Geriatric Syndrome; Introduction; What is a Geriatric Syndrome?; The Case for Osteoporotic Fractures as a Geriatric Syndrome
- Isbn
- 9783319259765
- Label
- Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches
- Title
- Osteoporosis in older persons
- Title remainder
- advances in pathophysiology and therapeutic approaches
- Statement of responsibility
- Gustavo Duque, Douglas P. Kiel, editors
- Language
- eng
- Summary
- This second edition brings together the latest information about the pathophysiology and new therapeutic alternatives for osteoporosis of advanced age. Written by highly recognised clinicians and basic scientists in the field of aging bone research, this book includes aspects of muscle and bone interaction focusing on the impact of age-related muscle loss (sarcopenia) on the pathogenesis of falls and fractures in older persons. Osteoporosis in Older Persons- Advances in Pathophysiology and Therapeutic Approach, Second Edition, aids the reader in understanding the mechanisms of senile osteoporosis with a practical approach to the treatment of its consequences. It is the perfect reference guide for geriatricians, gerontologists and bone biologists, as well as medical trainees.
- Cataloging source
- EBLCP
- Dewey number
-
- 616.7/16
- 610
- Index
- no index present
- LC call number
- RC931.O73
- Literary form
- non fiction
- Nature of contents
- dictionaries
- http://library.link/vocab/relatedWorkOrContributorName
-
- Duque, Gustavo
- Kiel, Douglas P
- http://library.link/vocab/subjectName
- Osteoporosis
- Label
- Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches, Gustavo Duque, Douglas P. Kiel, editors, (electronic book)
- Note
- Implications for Screening
- Antecedent source
- unknown
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
-
- Acknowledgements; Foreword; Preface; Contents; Contributors; 1: Biology of Bone; Overview; Bone Growth and Development; Bone Cell Differentiation; Osteoprogenitors, Osteoblasts, and Osteocytes; Regulators of Osteoblastic Cell Differentiation and Function; Wnt Signaling Molecules; Parathyroid Hormone; Vitamin D3; Estrogen; Bone Morphogenetic Proteins; Growth Hormone/Insulin-Like Growth Factor; Leptin/[beta] Adrenergic Receptors; Glucocorticoids; Thyroid Hormone; MicroRNAs; Monocytes/Macrophages and Osteoclastogenesis; Modulators of Osteoclastic Cell Differentiation and Function
- Bone Turnover Measurement of Bone Turnover; Bone Formation Markers; Bone Resorption Markers; Bone Turnover and Aging; Role of Bone and Bone Cells in Stem Cell Biology; References; 2: Aging and Bone; Introduction; Aging: A Definition; Contribution of Telomere Shortening to Age-Related Osteoblast Dysfunction; Other Aspects of Cellular Senescence; Aging and Bone Physiology; Skeletal Stem Cell (Also Known as Bone Marrow Stromal or Mesenchymal Stem Cells) (BMSC); The Inverse Relationship Between Adipocytes and Osteoblasts
- Biochemical Signaling Pathways, Genetic and Pharmaceutical Targets in Aging Why Fat?; Which Fat?; What Makes It Bone vs. Fat?; Apoptosis and the Aging Bone; References; 3: Calciotropic Hormones; Calcium; Vitamin D; Parathyroid Hormone; Calcitonin; Summary/Conclusion; References; 4: The Muscle-Bone Connection; Mechanical Coupling of Bones and Muscles; Beyond Mechanical Coupling: Bone-Muscle Developmental and Genetic Coupling; Genome Wide Association Studies (GWAS); Disease Conditions with Multiple Tissue Effects; The Unique Case of Fracture Healing
- Bones and Muscles as Endocrine Organs Bone as an Endocrine Organ; Muscle as an Endocrine Organ; Interplay Between Bones and Muscles as Endocrine Organs; Musculoskeletal Diseases: The Special Cases of Osteoporosis and Sarcopenia; Osteoporosis; Sarcopenia; The Role of Cartilage, Ligaments, and Tendons in Bone-Muscle Crosstalk; Crosstalk in MSK Development; Bone-Cartilage Crosstalk; Tendon-Muscle Crosstalk; Concluding Remarks and Future Directions; References; 5: Sex Steroids and Aging Bone; Introduction; Methodologic Issues; Sex Steroids and Age
- Sex Steroids and Bone Mineral Density (BMD) Women; Men; Sex Steroids, Volumetric BMD and Skeletal Structure; Sex Steroids and Fractures; Women; Men; Summary; References; 6: Animal Models for Aging Bone; Introduction; Normally Aged Animal Models; Genetic Manipulation and Accelerated Aging; Osteopenia Caused by Decrease in Bone Formation; The Aging Phenotype and Defects in Mineral Metabolism; What Mouse Models Teach; References; 7: Osteoporosis as a Geriatric Syndrome; Introduction; What is a Geriatric Syndrome?; The Case for Osteoporotic Fractures as a Geriatric Syndrome
- Control code
- SPR953662123
- Dimensions
- unknown
- Edition
- 2nd ed.
- Extent
- 1 online resource (299 p.)
- File format
- unknown
- Form of item
- online
- Isbn
- 9783319259765
- Level of compression
- unknown
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
- 10.1007/978-3-319-25976-5
- Quality assurance targets
- not applicable
- Reformatting quality
- unknown
- Sound
- unknown sound
- Specific material designation
- remote
- Label
- Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches, Gustavo Duque, Douglas P. Kiel, editors, (electronic book)
- Note
- Implications for Screening
- Antecedent source
- unknown
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
-
- Acknowledgements; Foreword; Preface; Contents; Contributors; 1: Biology of Bone; Overview; Bone Growth and Development; Bone Cell Differentiation; Osteoprogenitors, Osteoblasts, and Osteocytes; Regulators of Osteoblastic Cell Differentiation and Function; Wnt Signaling Molecules; Parathyroid Hormone; Vitamin D3; Estrogen; Bone Morphogenetic Proteins; Growth Hormone/Insulin-Like Growth Factor; Leptin/[beta] Adrenergic Receptors; Glucocorticoids; Thyroid Hormone; MicroRNAs; Monocytes/Macrophages and Osteoclastogenesis; Modulators of Osteoclastic Cell Differentiation and Function
- Bone Turnover Measurement of Bone Turnover; Bone Formation Markers; Bone Resorption Markers; Bone Turnover and Aging; Role of Bone and Bone Cells in Stem Cell Biology; References; 2: Aging and Bone; Introduction; Aging: A Definition; Contribution of Telomere Shortening to Age-Related Osteoblast Dysfunction; Other Aspects of Cellular Senescence; Aging and Bone Physiology; Skeletal Stem Cell (Also Known as Bone Marrow Stromal or Mesenchymal Stem Cells) (BMSC); The Inverse Relationship Between Adipocytes and Osteoblasts
- Biochemical Signaling Pathways, Genetic and Pharmaceutical Targets in Aging Why Fat?; Which Fat?; What Makes It Bone vs. Fat?; Apoptosis and the Aging Bone; References; 3: Calciotropic Hormones; Calcium; Vitamin D; Parathyroid Hormone; Calcitonin; Summary/Conclusion; References; 4: The Muscle-Bone Connection; Mechanical Coupling of Bones and Muscles; Beyond Mechanical Coupling: Bone-Muscle Developmental and Genetic Coupling; Genome Wide Association Studies (GWAS); Disease Conditions with Multiple Tissue Effects; The Unique Case of Fracture Healing
- Bones and Muscles as Endocrine Organs Bone as an Endocrine Organ; Muscle as an Endocrine Organ; Interplay Between Bones and Muscles as Endocrine Organs; Musculoskeletal Diseases: The Special Cases of Osteoporosis and Sarcopenia; Osteoporosis; Sarcopenia; The Role of Cartilage, Ligaments, and Tendons in Bone-Muscle Crosstalk; Crosstalk in MSK Development; Bone-Cartilage Crosstalk; Tendon-Muscle Crosstalk; Concluding Remarks and Future Directions; References; 5: Sex Steroids and Aging Bone; Introduction; Methodologic Issues; Sex Steroids and Age
- Sex Steroids and Bone Mineral Density (BMD) Women; Men; Sex Steroids, Volumetric BMD and Skeletal Structure; Sex Steroids and Fractures; Women; Men; Summary; References; 6: Animal Models for Aging Bone; Introduction; Normally Aged Animal Models; Genetic Manipulation and Accelerated Aging; Osteopenia Caused by Decrease in Bone Formation; The Aging Phenotype and Defects in Mineral Metabolism; What Mouse Models Teach; References; 7: Osteoporosis as a Geriatric Syndrome; Introduction; What is a Geriatric Syndrome?; The Case for Osteoporotic Fractures as a Geriatric Syndrome
- Control code
- SPR953662123
- Dimensions
- unknown
- Edition
- 2nd ed.
- Extent
- 1 online resource (299 p.)
- File format
- unknown
- Form of item
- online
- Isbn
- 9783319259765
- Level of compression
- unknown
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
- 10.1007/978-3-319-25976-5
- Quality assurance targets
- not applicable
- Reformatting quality
- unknown
- Sound
- unknown sound
- Specific material designation
- remote
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.liverpool.ac.uk/portal/Osteoporosis-in-older-persons--advances-in/bkaECcrRSwI/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.liverpool.ac.uk/portal/Osteoporosis-in-older-persons--advances-in/bkaECcrRSwI/">Osteoporosis in older persons : advances in pathophysiology and therapeutic approaches, Gustavo Duque, Douglas P. Kiel, editors, (electronic book)</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.liverpool.ac.uk/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.liverpool.ac.uk/">University of Liverpool</a></span></span></span></span></div>