Coverart for item
The Resource Platelet-vessel wall interactions in hemostasis and thrombosis, Rolando E. Rumbaut and Perumal Thiagarajan, (electronic book)

Platelet-vessel wall interactions in hemostasis and thrombosis, Rolando E. Rumbaut and Perumal Thiagarajan, (electronic book)

Label
Platelet-vessel wall interactions in hemostasis and thrombosis
Title
Platelet-vessel wall interactions in hemostasis and thrombosis
Statement of responsibility
Rolando E. Rumbaut and Perumal Thiagarajan
Creator
Contributor
Subject
Language
eng
Summary
Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions
Member of
Cataloging source
CaBNvSL
http://library.link/vocab/creatorDate
1964-
http://library.link/vocab/creatorName
Rumbaut, Rolando E.
Dewey number
616.135
Illustrations
illustrations
Index
no index present
LC call number
RC694.3
LC item number
.R856 2010
Literary form
non fiction
Nature of contents
  • dictionaries
  • abstracts summaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
Thiagarajan, Perumal.
Series statement
Colloquium series on integrated systems physiology, from molecule to function
Series volume
4
http://library.link/vocab/subjectName
  • Thrombosis
  • Hemostasis
  • Blood platelets
Target audience
  • adult
  • specialized
Label
Platelet-vessel wall interactions in hemostasis and thrombosis, Rolando E. Rumbaut and Perumal Thiagarajan, (electronic book)
Instantiates
Publication
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references (p. 45-67)
Color
multicolored
Contents
  • 1. Introduction -- 2. General characteristics of platelets -- Overview -- Platelet granules -- Alpha granules -- Dense granules -- Lysosomes -- Platelet adhesion molecules -- P-selectin -- Glycoprotein Ib/IX/V (GPIb/IX/V) -- Glycoprotein IIb/IIIa (GP IIb/IIIa) -- Collagen receptors -- G-protein-coupled receptors -- Thrombin -- Adenosine diphosphate (ADP) and adenosine triphosphate (ATP) -- Prostanoids --
  • 3. Platelet adhesion to vascular walls -- Adhesion to subendothelium following vascular injury -- Von Willebrand factor (vWF) -- Collagen -- Other subendothelial components -- Endogenous mechanisms preventing platelet adhesion to endothelium -- Nitric oxide -- Prostacyclin -- Ecto-adenosine diphosphatase (ADPase) -- Endothelial surface layer -- Mechanisms of platelet adhesion to endothelium -- Endothelial P-selectin-dependent mechanisms -- Endothelial vWF-dependent mechanisms -- Other mechanisms --
  • 4. Platelet aggregation -- Mechanisms of platelet aggregation -- Monitoring of platelet aggregation -- Ex vivo monitoring: platelet aggregometry -- In vivo monitoring of platelet aggregation --
  • 5. Platelet recruitment and blood coagulation -- Role of platelets -- Role of platelet-leukocyte interactions --
  • 6. Arterial, venous, and microvascular hemostasis/thrombosis -- Venous thrombosis -- Endothelial injury -- Hypercoagulability -- Stasis -- Coexistence of Virchow's triad components: cancer and thrombosis -- Arterial thrombosis -- Microvascular thrombosis --
  • 7. Summary -- Bibliography
Dimensions
unknown
Extent
1 electronic text (viii, 67 p. : ill.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615040391
Level of compression
unknown
Other physical details
digital file. ;
Quality assurance targets
unknown
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader
Label
Platelet-vessel wall interactions in hemostasis and thrombosis, Rolando E. Rumbaut and Perumal Thiagarajan, (electronic book)
Publication
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references (p. 45-67)
Color
multicolored
Contents
  • 1. Introduction -- 2. General characteristics of platelets -- Overview -- Platelet granules -- Alpha granules -- Dense granules -- Lysosomes -- Platelet adhesion molecules -- P-selectin -- Glycoprotein Ib/IX/V (GPIb/IX/V) -- Glycoprotein IIb/IIIa (GP IIb/IIIa) -- Collagen receptors -- G-protein-coupled receptors -- Thrombin -- Adenosine diphosphate (ADP) and adenosine triphosphate (ATP) -- Prostanoids --
  • 3. Platelet adhesion to vascular walls -- Adhesion to subendothelium following vascular injury -- Von Willebrand factor (vWF) -- Collagen -- Other subendothelial components -- Endogenous mechanisms preventing platelet adhesion to endothelium -- Nitric oxide -- Prostacyclin -- Ecto-adenosine diphosphatase (ADPase) -- Endothelial surface layer -- Mechanisms of platelet adhesion to endothelium -- Endothelial P-selectin-dependent mechanisms -- Endothelial vWF-dependent mechanisms -- Other mechanisms --
  • 4. Platelet aggregation -- Mechanisms of platelet aggregation -- Monitoring of platelet aggregation -- Ex vivo monitoring: platelet aggregometry -- In vivo monitoring of platelet aggregation --
  • 5. Platelet recruitment and blood coagulation -- Role of platelets -- Role of platelet-leukocyte interactions --
  • 6. Arterial, venous, and microvascular hemostasis/thrombosis -- Venous thrombosis -- Endothelial injury -- Hypercoagulability -- Stasis -- Coexistence of Virchow's triad components: cancer and thrombosis -- Arterial thrombosis -- Microvascular thrombosis --
  • 7. Summary -- Bibliography
Dimensions
unknown
Extent
1 electronic text (viii, 67 p. : ill.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615040391
Level of compression
unknown
Other physical details
digital file. ;
Quality assurance targets
unknown
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader

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