Coverart for item
The Resource Robustness and evolvability in living systems, Andreas Wagner, (electronic book)

Robustness and evolvability in living systems, Andreas Wagner, (electronic book)

Label
Robustness and evolvability in living systems
Title
Robustness and evolvability in living systems
Statement of responsibility
Andreas Wagner
Creator
Subject
Language
eng
Summary
"All living things are remarkably complex, yet their DNA is unstable, undergoing countless random mutations over generations. Despite this instability, most animals do not grow two heads or die, plants continue to thrive, and bacteria continue to divide. Robustness and Evolvability in Living Systems tackles this perplexing paradox. The book explores why genetic changes do not cause organisms to fail catastrophically and how evolution shapes organisms' robustness. Andreas Wagner looks at this problem from the ground up, starting with the alphabet of DNA, the genetic code, RNA, and protein molecules, moving on to genetic networks and embryonic development and working his way up to whole organisms. He then develops an evolutionary explanation for robustness." "Unparalled in its field, this book offers the most detailed analysis available of all facets of robustness within organisms. It will appeal not only to biologists but also to engineers interested in the design of robust systems and to social scientists concerned with robustness in human communities and populations."--BOOK JACKET
Cataloging source
DLC
http://library.link/vocab/creatorDate
1967 January 26-
http://library.link/vocab/creatorName
Wagner, Andreas
Illustrations
illustrations
Index
index present
Literary form
non fiction
Nature of contents
bibliography
Series statement
Princeton studies in complexity
http://library.link/vocab/subjectName
  • Molecular evolution
  • Mutation (Biology)
  • Biological systems
  • Robust control
Label
Robustness and evolvability in living systems, Andreas Wagner, (electronic book)
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references (pages [323]-358) and index
Carrier category
online resource
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type MARC source
rdacontent
Contents
Introduction -- The genetic alphabet -- The genetic code -- RNA structure -- Proteins and point mutations -- Proteins and recombination -- Regulatory DNA regions and their reorganization in evolution -- Metabolic pathways -- Metabolic networks -- Drosophila segmentation and other gene regulatory networks -- Phenotypic traits, cryptic variation, and human diseases -- The many ways of building the same body -- Neutral spaces -- Evolvability and neutral mutations -- Redundancy of parts or distributed robustness? -- Robustness as an evolved adaptation to mutations -- Robustness as an evolved adapatation to environmental change and noise -- Robustness and fragility: advantages to variation and trade-offs -- Robustness in natural systems and self-organization -- Robustness in man-made systems
Control code
ebr10782425
Dimensions
unknown
Extent
1 online resource (384 pages)
Form of item
online
Isbn
9781400849383
Media category
computer
Media MARC source
rdamedia
Note
Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.
Original version note
Original electronic resource
Other physical details
illustrations.
Reproduction note
Electronic resource.
Specific material designation
remote
Label
Robustness and evolvability in living systems, Andreas Wagner, (electronic book)
Publication
Copyright
Bibliography note
Includes bibliographical references (pages [323]-358) and index
Carrier category
online resource
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type MARC source
rdacontent
Contents
Introduction -- The genetic alphabet -- The genetic code -- RNA structure -- Proteins and point mutations -- Proteins and recombination -- Regulatory DNA regions and their reorganization in evolution -- Metabolic pathways -- Metabolic networks -- Drosophila segmentation and other gene regulatory networks -- Phenotypic traits, cryptic variation, and human diseases -- The many ways of building the same body -- Neutral spaces -- Evolvability and neutral mutations -- Redundancy of parts or distributed robustness? -- Robustness as an evolved adaptation to mutations -- Robustness as an evolved adapatation to environmental change and noise -- Robustness and fragility: advantages to variation and trade-offs -- Robustness in natural systems and self-organization -- Robustness in man-made systems
Control code
ebr10782425
Dimensions
unknown
Extent
1 online resource (384 pages)
Form of item
online
Isbn
9781400849383
Media category
computer
Media MARC source
rdamedia
Note
Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.
Original version note
Original electronic resource
Other physical details
illustrations.
Reproduction note
Electronic resource.
Specific material designation
remote

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