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The Resource Skeletal muscle & muscular dystrophy : a visual approach, Donald A. Fischman, (electronic book)

Skeletal muscle & muscular dystrophy : a visual approach, Donald A. Fischman, (electronic book)

Label
Skeletal muscle & muscular dystrophy : a visual approach
Title
Skeletal muscle & muscular dystrophy
Title remainder
a visual approach
Statement of responsibility
Donald A. Fischman
Creator
Subject
Language
eng
Summary
Histologically, muscle is conveniently divided into two groups, striated and nonstriated, based on whether the cells exhibit cross-striations in the light microscope (Figure 3). Smooth muscle is involuntary--its contraction is controlled by the autonomic nervous system. Striated muscle includes both cardiac (involuntary) and skeletal (voluntary). The former is innervated by visceral efferent fibers of the autonomic nervous system, whereas the latter is innervated by somatic efferent fibers, most of which have their cell bodies in the ventral, motor horn of the spinal cord. Smooth muscle is designed to have slow, relatively sustained contractions, while striated muscle contracts rapidly and usually phasically. Both cardiac and smooth muscle cells are mononucleated, whereas skeletal muscle cells (fibers) are multinucleated. [In aging hearts or hypertrophied hearts, cardiac muscle cells are often binucleated.] Multinucleation of skeletal muscle arises during development by the cytoplasmic fusion of muscle precursor cells, myoblasts. Adult skeletal muscle cells do not divide; that is also true of most cardiac myocytes. However, skeletal muscle exhibits a considerable amount of regeneration after injury. This is because adult skeletal muscle contains a stem cell, the satellite cell, which lies beneath the basement membrane surrounding the muscle fibers. [The multinucleation of cardiac muscle arises from karyokinesis without cytokinesis.] A diagrammatic series of enlargements of skeletal muscle are shown in Figure 4. A bundle of muscle fibers (fasciculus) is cut from the deltoid muscle. Each muscle cell is termed a myofiber or muscle fiber. Each muscle fiber contains contractile organelles termed myofibrils, which contain the contractile units of muscle termed sarcomeres. The sarcomeres are composed of myofilaments, which in turn are composed of contractile proteins. Muscle connective tissue layers are organized in concentric layers that are important in the entry and exit of vessels and nerves to and from the tissue. These are shown in Figure 5. The outermost layer is the epimysium or muscle sheath. Connective tissue septae (perimysium) run radially into the muscle tissue, dividing it into muscle fascicles. The deepest layer, surrounding each of the muscle fibers is the endomysium. The endomysium is in direct contact with a basal lamina that ensheathes each muscle fiber. It surrounds the plasma membrane of the muscle fiber termed the sarcolemma
Member of
Cataloging source
CaBNvSL
http://library.link/vocab/creatorName
Fischman, Donald.
Dewey number
612.74
Illustrations
illustrations
Index
index present
LC call number
QP321
LC item number
.F577 2009
Literary form
non fiction
Nature of contents
  • dictionaries
  • abstracts summaries
  • bibliography
Series statement
Colloquium series on the cell biology of medicine
Series volume
2
http://library.link/vocab/subjectName
  • Muscles
  • Muscular Dystrophy
Target audience
  • adult
  • specialized
Label
Skeletal muscle & muscular dystrophy : a visual approach, Donald A. Fischman, (electronic book)
Instantiates
Publication
Note
Part of: 'Colloquium digital library of life sciences'
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references (p. 43) and index
Color
multicolored
Contents
Introduction to the cell biology of medicine -- Introduction -- The muscle cell (myofiber) -- The sarcomere -- The myosin molecule -- Regulation of muscle contraction -- The sarcoplasmic reticulum -- Muscle fiber types -- The myotendon junction -- The satellite cell -- Muscular dystrophy -- Recommended readings -- Series editor biography -- Index
Dimensions
unknown
Extent
1 electronic text (ix, 56 p. : ill.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615040049
Level of compression
unknown
Other physical details
digital file. ;
Quality assurance targets
unknown
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader
Label
Skeletal muscle & muscular dystrophy : a visual approach, Donald A. Fischman, (electronic book)
Publication
Note
Part of: 'Colloquium digital library of life sciences'
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references (p. 43) and index
Color
multicolored
Contents
Introduction to the cell biology of medicine -- Introduction -- The muscle cell (myofiber) -- The sarcomere -- The myosin molecule -- Regulation of muscle contraction -- The sarcoplasmic reticulum -- Muscle fiber types -- The myotendon junction -- The satellite cell -- Muscular dystrophy -- Recommended readings -- Series editor biography -- Index
Dimensions
unknown
Extent
1 electronic text (ix, 56 p. : ill.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615040049
Level of compression
unknown
Other physical details
digital file. ;
Quality assurance targets
unknown
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader

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