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The Resource The actin cytoskeleton in cell motility, cancer, and infection, Joel D. Pardee, (electronic book)

The actin cytoskeleton in cell motility, cancer, and infection, Joel D. Pardee, (electronic book)

Label
The actin cytoskeleton in cell motility, cancer, and infection
Title
The actin cytoskeleton in cell motility, cancer, and infection
Statement of responsibility
Joel D. Pardee
Creator
Subject
Language
eng
Summary
By now it is abundantly clear that the cells of our bodies have the ability to move because of their actin cytoskeleton. From the earliest cell migrations in the embryo that serve to form the primordial tissue layers to the outgrowth of neurons, the contractions of our heart and skeletal muscles, and the metastasis of cancer cells, it is the regulated action of the actin cytoskeleton that propels our various motions. In this chapter we will examine the biochemical and cell biological mechanisms that control actin-based cell motility. We will see that cell migration along a substratum occurs in three fundamental phases that are exquisitely orchestrated in sequence. Cell migration occurs by an initial extension of the front edge of the cell, followed closely by contraction of the cell's rear end to push cytoplasm into the newly formed extension. As the cell's new leading edge extends, attachment sites are assembled on the cell floor, and extend through the plasma membrane to couple the migrating cell to the underlying surface. How the cell knows where to go, when to detach and reattach during the migration, and how to keep each process under strict control is a story well worth hearing, because it is motility and adhesion that make a multicellular life such as ours possible
Member of
Cataloging source
CaBNvSL
http://library.link/vocab/creatorName
Pardee, Joel D.
Dewey number
574.8764
Illustrations
illustrations
Index
no index present
LC call number
QH647
LC item number
.P273 2010
Literary form
non fiction
Nature of contents
  • dictionaries
  • abstracts summaries
  • bibliography
Series statement
Colloquium series on the cell biology of medicine
Series volume
3
http://library.link/vocab/subjectName
  • Cells
  • Actin
  • Cytoskeleton
  • Cell Movement
Target audience
  • adult
  • specialized
Label
The actin cytoskeleton in cell motility, cancer, and infection, Joel D. Pardee, (electronic book)
Instantiates
Publication
Note
Part of: 'Colloquium digital library of life sciences'
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references (p. 57)
Color
multicolored
Contents
The cytoskeleton -- How cells move -- Regulation of the actin cytoskeleton -- The role of myosin in cell motility -- The role of cell adhesion in cell motility -- Recommended readings
Dimensions
unknown
Extent
1 electronic text (xi, 57 p. : ill.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615040063
Level of compression
unknown
Other physical details
digital file. ;
Quality assurance targets
not applicable
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader
Label
The actin cytoskeleton in cell motility, cancer, and infection, Joel D. Pardee, (electronic book)
Publication
Note
Part of: 'Colloquium digital library of life sciences'
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references (p. 57)
Color
multicolored
Contents
The cytoskeleton -- How cells move -- Regulation of the actin cytoskeleton -- The role of myosin in cell motility -- The role of cell adhesion in cell motility -- Recommended readings
Dimensions
unknown
Extent
1 electronic text (xi, 57 p. : ill.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615040063
Level of compression
unknown
Other physical details
digital file. ;
Quality assurance targets
not applicable
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader

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