Coverart for item
The Resource The evaluation of surrogate endpoints, edited by Tomasz Burzykowski, Geert Molenberghs, Marc Buyse, (electronic book)

The evaluation of surrogate endpoints, edited by Tomasz Burzykowski, Geert Molenberghs, Marc Buyse, (electronic book)

Label
The evaluation of surrogate endpoints
Title
The evaluation of surrogate endpoints
Statement of responsibility
edited by Tomasz Burzykowski, Geert Molenberghs, Marc Buyse
Contributor
Subject
Language
eng
Summary
The identification and use of surrogate endpoints, i.e., measures that can replace or supplement other endpoints in evaluations of experimental treatments or other interventions, is a general strategy that has stimulated both enthusiasm and scepticism. This book offers a balanced account on this controversial topic
Member of
Cataloging source
COO
Dewey number
610/.72/4
Illustrations
illustrations
Index
index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Molenberghs, Geert
  • Buyse, Marc E
  • Burzykowski, Tomasz
http://library.link/vocab/subjectName
  • Clinical trials
  • Drugs
  • Biological Markers
  • Clinical Trials
  • Drug Evaluation
Label
The evaluation of surrogate endpoints, edited by Tomasz Burzykowski, Geert Molenberghs, Marc Buyse, (electronic book)
Instantiates
Publication
Bibliography note
Includes bibliographical references (p. 367-399) and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Setting the Scene -- Regulatory Aspects in Using Surrogate Markers in Clinical Trials -- Notation and Motivating Studies -- The History of Surrogate Marker Validation -- Validation Using Single-Trial Data: Mixed Binary and Continuous Outcomes -- A Meta-Analytic Validation Framework for Contiuous Outcomes -- The Choice of Units -- Extensions of the Meta-Analytic Approach to Surrogate Endpoints -- Meta-Analytic Validation with Binary Outcomes -- Validation in the Case of Two Failure-Time Endpoints -- An Ordinal Surrogate for a Survival True Endpoint -- A Combination of Longitudinal and Survival Endpoints -- Repeated Measures and Surrogate Marker Validation -- Bayesian Evaluation of Surrogate Endpoints -- Surrogate Marker Validation in Mental Health -- The Evaluation of Surrogate Endpoints in Practice: Experience in HIV -- An Alternative Measure for Meta-Analytic Surrogate Marker Validation -- Discussion: Surrogate Endpoint Definition and Evaluation --The Promise and Peril of Surrogate End Points in Cancer Research
Control code
SPR64399892
Extent
xxiii, 408 p.
Form of item
online
Isbn
9780387202778
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
ill.
Specific material designation
remote
Label
The evaluation of surrogate endpoints, edited by Tomasz Burzykowski, Geert Molenberghs, Marc Buyse, (electronic book)
Publication
Bibliography note
Includes bibliographical references (p. 367-399) and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Setting the Scene -- Regulatory Aspects in Using Surrogate Markers in Clinical Trials -- Notation and Motivating Studies -- The History of Surrogate Marker Validation -- Validation Using Single-Trial Data: Mixed Binary and Continuous Outcomes -- A Meta-Analytic Validation Framework for Contiuous Outcomes -- The Choice of Units -- Extensions of the Meta-Analytic Approach to Surrogate Endpoints -- Meta-Analytic Validation with Binary Outcomes -- Validation in the Case of Two Failure-Time Endpoints -- An Ordinal Surrogate for a Survival True Endpoint -- A Combination of Longitudinal and Survival Endpoints -- Repeated Measures and Surrogate Marker Validation -- Bayesian Evaluation of Surrogate Endpoints -- Surrogate Marker Validation in Mental Health -- The Evaluation of Surrogate Endpoints in Practice: Experience in HIV -- An Alternative Measure for Meta-Analytic Surrogate Marker Validation -- Discussion: Surrogate Endpoint Definition and Evaluation --The Promise and Peril of Surrogate End Points in Cancer Research
Control code
SPR64399892
Extent
xxiii, 408 p.
Form of item
online
Isbn
9780387202778
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
ill.
Specific material designation
remote

Library Locations

Processing Feedback ...