Coverart for item
The Resource Therapeutic applications of RNAi : methods and protocols, edited by John F. Reidhaar-Olson, Cristina M. Rondinone, (electronic book)

Therapeutic applications of RNAi : methods and protocols, edited by John F. Reidhaar-Olson, Cristina M. Rondinone, (electronic book)

Label
Therapeutic applications of RNAi : methods and protocols
Title
Therapeutic applications of RNAi
Title remainder
methods and protocols
Statement of responsibility
edited by John F. Reidhaar-Olson, Cristina M. Rondinone
Contributor
Subject
Genre
Language
eng
Summary
The phenomenon of RNA interference has rapidly moved from groundbreaking scientific discovery to promising therapeutic approach. However, even as RNAi-based drugs enter the clinic, significant challenges remain, particulary in the area of delivery. Therapeutic Applications of RNAi provides detailed protocols in key areas of current focus, including testing of delivery vehicles, identification of appropriate model systems, and evaluation of the effects of RNAi in vivo. Produced by a team of internationally renowned authors, the volume describes the therapeutic applications of RNAi and potential pitfalls in oncology, viral infections and CNS disease, using a variety of delivery methods, including liposomes, peptide-based nanoparticles, polycationic polymers, and viral vehicles. Written in the highly successful Methods in Molecular Biology series format, the chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Therapeutic Applications of RNAi is an ideal guide for scientists attempting to solve the numerous challenges in this field and revolutionize the treatment of disease
Member of
Cataloging source
CUS
Dewey number
572.88
Illustrations
illustrations
Index
index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Reidhaar-Olson, John F.
  • Rondinone, Cristina M.
http://library.link/vocab/subjectName
  • Small interfering RNA
  • ARN interférence
  • RNA Interference
  • Drug Discovery
Label
Therapeutic applications of RNAi : methods and protocols, edited by John F. Reidhaar-Olson, Cristina M. Rondinone, (electronic book)
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Development and application of a dual-purpose nanoparticle platform for delivery and imaging of siRNA in tumors / Z. Medarova ... [et al.] -- Targeted gene silencing into solid tumors with electrically mediated siRNA delivery / M. Golzio ... [et al.] -- Liposomal siRNA for ovarian cancer / L.S. Mangala ... [et al.] -- Therapeutic applications of RNAi for silencing virus replication / R.A. Tripp and S.M. Tompkins -- RNAi in the malaria vector, Anopheles gambiae / F. Catteruccia and E.A. Levashina -- RNAi using a chitosan/siRNA nanoparticle system: in vitro and in vivo applications / M.O. Andersen, K.A. Howard and J. Kjems -- Lentiviral and adeno-associated vector-based therapy for motor neuron disease through RNAi / C. Towne and P. Aebischer -- Studying autoimmunity by in vivo RNA interference / S. Kissler -- Transcriptional gene silencing using small RNAs / D.H. Kim and J.J. Rossi -- Alternative splicing as a therapeutic target for human diseases / K.J. Dery ... [et al.]
Control code
SPR436089400
Form of item
  • online
  • electronic
Isbn
9781603272957
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
Label
Therapeutic applications of RNAi : methods and protocols, edited by John F. Reidhaar-Olson, Cristina M. Rondinone, (electronic book)
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Development and application of a dual-purpose nanoparticle platform for delivery and imaging of siRNA in tumors / Z. Medarova ... [et al.] -- Targeted gene silencing into solid tumors with electrically mediated siRNA delivery / M. Golzio ... [et al.] -- Liposomal siRNA for ovarian cancer / L.S. Mangala ... [et al.] -- Therapeutic applications of RNAi for silencing virus replication / R.A. Tripp and S.M. Tompkins -- RNAi in the malaria vector, Anopheles gambiae / F. Catteruccia and E.A. Levashina -- RNAi using a chitosan/siRNA nanoparticle system: in vitro and in vivo applications / M.O. Andersen, K.A. Howard and J. Kjems -- Lentiviral and adeno-associated vector-based therapy for motor neuron disease through RNAi / C. Towne and P. Aebischer -- Studying autoimmunity by in vivo RNA interference / S. Kissler -- Transcriptional gene silencing using small RNAs / D.H. Kim and J.J. Rossi -- Alternative splicing as a therapeutic target for human diseases / K.J. Dery ... [et al.]
Control code
SPR436089400
Form of item
  • online
  • electronic
Isbn
9781603272957
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote

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