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The Resource Viral vectors for gene therapy : methods and protocols, edited by Curtis A. Machida, (electronic book)

Viral vectors for gene therapy : methods and protocols, edited by Curtis A. Machida, (electronic book)

Label
Viral vectors for gene therapy : methods and protocols
Title
Viral vectors for gene therapy
Title remainder
methods and protocols
Statement of responsibility
edited by Curtis A. Machida
Contributor
Subject
Genre
Language
eng
Summary
The promise of gene therapy can be realized only if workable vectors can be found to deliver therapeutic genes. In Viral Vectors for Gene Therapy: Methods and Protocols, leading researchers from academia and biotechnology describe proven molecular methods for the construction, development, and use of virus vectors for gene transfer and gene therapy. Offering detailed step-by-step instructions to ensure successful results, these experts detail the use of herpes viruses, adenoviruses, adeno-associated viruses, simple and complex retroviruses, including lentiviruses, and other virus systems for vector development and gene transfer. Additional chapters demonstrate the use of virus vectors in the brain and central nervous system. Each protocol includes a discussion of the principles involved, numerous charts and tables, ample references, and notes on possible problems, troubleshooting, and alternative procedures. Comprehensive and highly practical, Viral Vectors for Gene Therapy: Methods and Protocols provides not only researchers with the basic tools needed to design targeted gene delivery vectors, but also clinicians with an understanding of how to apply viral vectors to the treatment of genetic disorders
Member of
Additional physical form
Also issued in print.
Cataloging source
COO
Dewey number
616/.042
Illustrations
illustrations
Index
index present
LC call number
RB155.8
LC item number
.V54 2003
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
Machida, Curtis A.
Series statement
Methods in molecular medicine
Series volume
76
http://library.link/vocab/subjectName
  • Gene therapy
  • Genetic vectors
  • Transfection
  • Viral genetics
  • HEALTH & FITNESS
  • MEDICAL
  • Electronic books
Label
Viral vectors for gene therapy : methods and protocols, edited by Curtis A. Machida, (electronic book)
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Use of the herpes simplex viral genome to construct gene therapy vectors / E.A. Burton ... [et al.] -- Construction of multiply disabled herpes simplex viral vectors for gene delivery to the nervous system / C.E. Lilley and R.S. Coffin -- Improved HSV-1 amplicon packaging system using ICP27-deleted, oversized HSV-1 BAC DNA / Y. Saeki, X.O. Breakefield and E.A. Chiocca -- Herpes simplex amplicon vectors / C.J. Link, N.N. Vahanian and S. Wang -- Strategies to adapt adenoviral vectors for targeted delivery / C.R. O'Riordan, A. Song and J. Lanciotti -- Use of recombinant adenovirus for gene transfer into the rat brain. Evaluation of gene transfer efficiency, toxicity, and inflammatory and immune reactions / A. Hurtado-Lorenzo ... [et al.] -- Generation of adenovirus vectors devoid of all viral genes by recombination between inverted repeats / H. Stecher ... [et al.] -- Packaging cell lines for generating replication-defective and gutted adenoviral vectors / J.S. Chamberlain, C. Barjot and J. Scott -- Improving the transcriptional regulation of genes delivered by adenovirus vectors / S. Rubinchik ... [et al.] -- Targeted integration by adeno-associated virus / M.D. Weitzman ... [et al.] -- Development and optimization of adeno-associated virus vector transfer into the central nervous system / M.J. During ... [et al.] -- A method for helper virus-free production of adeno-associated virus vectors / R.F. Collaco and J.P. Trempe -- Novel tools for production and purification of recombinant adeno-associated viral vectors / J.D. Harris, S.G. Beattie and J.G. Dickson -- Recombinant adeno-associated viral vector types 4 and 5. Preparation and application for CNS gene transfer / B.L. Davidson and J.A. Chiorini -- Trans-splicing vectors expand the packaging limits of adeno-associated virus for gene therapy applications / D. Duan ... [et al.] -- Generation of retroviral packaging and producer cell lines for large-scale vector production with improved safety and titer / T.W. Dubensky, Jr. and S.L. Sauter -- An ecdysone-inducible expression system for use with retroviruses / K. Morse and J. Olsen -- In vivo infection of mice by replication-competent MLV-based retroviral vectors / E. Bachrach ... [et al.] -- Development of simian retroviral vectors for gene delivery / B. Li and C.A. Machida -- Self-inactivating lentiviral vectors and a sensitive Cre-loxP reporter system / L.J. Chang and A.K. Zaiss -- Lentiviral vectors for gene transfer to the central nervous system. Applications in lysosomal storage disease animal models / D.J. Watson and J.H. Wolfe -- A highly efficient gene delivery system derived from feline immunodeficiency virus (FIV) / S.L. Sauter, M. Gasmi and T.W. Dubensky, Jr. -- A multigene lentiviral vector system based on differential splicing / Y. Zhu and V. Planelles -- Production of trans-lentiviral vector with predictable safety / J.C. Kappes, X. Wu and J.K. Wakefield -- Human immunodeficiency virus type 1-based vectors for gene delivery to human hematopoietic stem cells / A. Ramezani and R.G. Hawley -- Semliki Forest virus vectors for gene transfer / J. Wahlfors and R.A. Morgan -- Semliki Forest virus (SFV) vectors in neurobiology and gene therapy / K. Lundstrom and M.U. Ehrengruber -- Semliki Forest virus vectors for large-scale production of recombinant proteins / K. Lundstrom -- Development of foamy virus vectors / G. Vassilopoulos, N.C. Josephson and G. Trobridge -- Poxviral/retroviral chimeric vectors allow cytoplasmic production of transducing defective retroviral particles / G.W. Holzer and F.G. Falkner
Control code
SPR52434454
Dimensions
unknown
Extent
1 online resource (xv, 589 p.)
Form of item
online
Isbn
9781592593040
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
ill.
Specific material designation
remote
Label
Viral vectors for gene therapy : methods and protocols, edited by Curtis A. Machida, (electronic book)
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Use of the herpes simplex viral genome to construct gene therapy vectors / E.A. Burton ... [et al.] -- Construction of multiply disabled herpes simplex viral vectors for gene delivery to the nervous system / C.E. Lilley and R.S. Coffin -- Improved HSV-1 amplicon packaging system using ICP27-deleted, oversized HSV-1 BAC DNA / Y. Saeki, X.O. Breakefield and E.A. Chiocca -- Herpes simplex amplicon vectors / C.J. Link, N.N. Vahanian and S. Wang -- Strategies to adapt adenoviral vectors for targeted delivery / C.R. O'Riordan, A. Song and J. Lanciotti -- Use of recombinant adenovirus for gene transfer into the rat brain. Evaluation of gene transfer efficiency, toxicity, and inflammatory and immune reactions / A. Hurtado-Lorenzo ... [et al.] -- Generation of adenovirus vectors devoid of all viral genes by recombination between inverted repeats / H. Stecher ... [et al.] -- Packaging cell lines for generating replication-defective and gutted adenoviral vectors / J.S. Chamberlain, C. Barjot and J. Scott -- Improving the transcriptional regulation of genes delivered by adenovirus vectors / S. Rubinchik ... [et al.] -- Targeted integration by adeno-associated virus / M.D. Weitzman ... [et al.] -- Development and optimization of adeno-associated virus vector transfer into the central nervous system / M.J. During ... [et al.] -- A method for helper virus-free production of adeno-associated virus vectors / R.F. Collaco and J.P. Trempe -- Novel tools for production and purification of recombinant adeno-associated viral vectors / J.D. Harris, S.G. Beattie and J.G. Dickson -- Recombinant adeno-associated viral vector types 4 and 5. Preparation and application for CNS gene transfer / B.L. Davidson and J.A. Chiorini -- Trans-splicing vectors expand the packaging limits of adeno-associated virus for gene therapy applications / D. Duan ... [et al.] -- Generation of retroviral packaging and producer cell lines for large-scale vector production with improved safety and titer / T.W. Dubensky, Jr. and S.L. Sauter -- An ecdysone-inducible expression system for use with retroviruses / K. Morse and J. Olsen -- In vivo infection of mice by replication-competent MLV-based retroviral vectors / E. Bachrach ... [et al.] -- Development of simian retroviral vectors for gene delivery / B. Li and C.A. Machida -- Self-inactivating lentiviral vectors and a sensitive Cre-loxP reporter system / L.J. Chang and A.K. Zaiss -- Lentiviral vectors for gene transfer to the central nervous system. Applications in lysosomal storage disease animal models / D.J. Watson and J.H. Wolfe -- A highly efficient gene delivery system derived from feline immunodeficiency virus (FIV) / S.L. Sauter, M. Gasmi and T.W. Dubensky, Jr. -- A multigene lentiviral vector system based on differential splicing / Y. Zhu and V. Planelles -- Production of trans-lentiviral vector with predictable safety / J.C. Kappes, X. Wu and J.K. Wakefield -- Human immunodeficiency virus type 1-based vectors for gene delivery to human hematopoietic stem cells / A. Ramezani and R.G. Hawley -- Semliki Forest virus vectors for gene transfer / J. Wahlfors and R.A. Morgan -- Semliki Forest virus (SFV) vectors in neurobiology and gene therapy / K. Lundstrom and M.U. Ehrengruber -- Semliki Forest virus vectors for large-scale production of recombinant proteins / K. Lundstrom -- Development of foamy virus vectors / G. Vassilopoulos, N.C. Josephson and G. Trobridge -- Poxviral/retroviral chimeric vectors allow cytoplasmic production of transducing defective retroviral particles / G.W. Holzer and F.G. Falkner
Control code
SPR52434454
Dimensions
unknown
Extent
1 online resource (xv, 589 p.)
Form of item
online
Isbn
9781592593040
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
ill.
Specific material designation
remote

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