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The Resource Wnt/[beta]-catenin signaling in vertebrate posterior neural development, Yaniv M. Elkouby, Dale Frank, (electronic book)

Wnt/[beta]-catenin signaling in vertebrate posterior neural development, Yaniv M. Elkouby, Dale Frank, (electronic book)

Label
Wnt/[beta]-catenin signaling in vertebrate posterior neural development
Title
Wnt/[beta]-catenin signaling in vertebrate posterior neural development
Statement of responsibility
Yaniv M. Elkouby, Dale Frank
Title variation
Wnt/Ý-catenin signalling in vertebrate posterior neural development
Creator
Contributor
Subject
Language
eng
Summary
The Wnt/[beta]-catenin signaling pathway is a key regulator of cell fate specification, differentiation, and growth in multiple systems throughout the animal kingdom. In vertebrate posterior neural development, Wnt/[beta]-catenin signaling controls this complex multistep process. It initially induces the posterior regions of the nervous system, including the mid-hindbrain border, hindbrain, spinal cord and neural crest, and then subsequently fine-tunes the pattern of each region and determines the different cell fates within them. In this review, we explore the function of the Wnt/[beta]-catenin pathway during the formation of these specific posterior neural regions. We have examined the important transcriptional targets of the Wnt/[beta]-catenin pathway acting downstream to mediate its morphogenetic activity. Different regulatory networks are activated in different posterior neural regions, and these networks induce specific neural cell types in each region. Eludidating how each of these networks specify different cell fates is crucial for understanding the basic tenets of how Wnt morphogenetic activity induces the posterior nervous system during the earliest stages of vertebrate development
Member of
Cataloging source
CaBNvSL
http://library.link/vocab/creatorName
Elkouby, Yaniv M.
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
Frank, Dale
Series statement
Developmental biology
Series volume
4
http://library.link/vocab/subjectName
  • Wnt proteins
  • Wnt genes
  • Developmental neurobiology
Target audience
adult
Label
Wnt/[beta]-catenin signaling in vertebrate posterior neural development, Yaniv M. Elkouby, Dale Frank, (electronic book)
Instantiates
Publication
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references (p. 61-79)
Color
multicolored
Contents
Introduction -- Making the neural rear -- Wnt morphogenetic activity in neural posterior induction -- Induction of the midbrain-hindbrain border -- Induction of the hindbrain -- Induction of the spinal cord -- Downstream of wnt: hindbrain or spinal cord -- Neural crest induction -- Anti-Wnt anterior determinants -- The role of mesoderm and specific Wnt ligands in neural patterning -- Concluding remarks -- References
Dimensions
unknown
Extent
1 electronic text (vii, 79 p. : ill.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615040551
Level of compression
unknown
Other physical details
digital file. ;
Quality assurance targets
unknown
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader
Label
Wnt/[beta]-catenin signaling in vertebrate posterior neural development, Yaniv M. Elkouby, Dale Frank, (electronic book)
Publication
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references (p. 61-79)
Color
multicolored
Contents
Introduction -- Making the neural rear -- Wnt morphogenetic activity in neural posterior induction -- Induction of the midbrain-hindbrain border -- Induction of the hindbrain -- Induction of the spinal cord -- Downstream of wnt: hindbrain or spinal cord -- Neural crest induction -- Anti-Wnt anterior determinants -- The role of mesoderm and specific Wnt ligands in neural patterning -- Concluding remarks -- References
Dimensions
unknown
Extent
1 electronic text (vii, 79 p. : ill.)
File format
multiple file formats
Form of item
electronic
Isbn
9781615040551
Level of compression
unknown
Other physical details
digital file. ;
Quality assurance targets
unknown
Reformatting quality
access
Specific material designation
remote
System details
System requirements: Adobe Acrobat reader

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