Non-neuronal mechanisms of brain damage and repair after stroke, Jun Chen, John H. Zhang, Xiaoming Hu, editors, (electronic book)

Resource Information

The instance Non-neuronal mechanisms of brain damage and repair after stroke, Jun Chen, John H. Zhang, Xiaoming Hu, editors, (electronic book) represents a material embodiment of a distinct intellectual or artistic creation found in Sydney Jones Library, University of Liverpool. This resource is a combination of several types including: Instance, Electronic.

Image

http://covers.openlibrary.org/b/isbn/9783319323374-M.jpg?default=false

Label

Non-neuronal mechanisms of brain damage and repair after stroke, Jun Chen, John H. Zhang, Xiaoming Hu, editors, (electronic book)

Medium

electronic book

Statement of responsibility

Jun Chen, John H. Zhang, Xiaoming Hu, editors

Instantiates

• Non-neuronal mechanisms of brain damage and repair after stroke

Publication

• Switzerland, Springer, 2016

Antecedent source

unknown

Carrier category

online resource

Carrier category code

• cr

Carrier MARC source

rdacarrier

Color

multicolored

Content category

text

Content type code

• txt

Content type MARC source

rdacontent

Contents

• Introduction: Nonneuronal Mechanisms and Targets for Stroke; Contents; Contributors; Part I: Microvascular Integrity in Stroke; Structural Alterations to the Endothelial Tight Junction Complex During Stroke; 1 Introduction; 2 Normal BBB Structure and Function.; 3 Alterations in BBB Function After Stroke; 4 Alterations to TJ Structure After Stroke; 5 Signaling Mechanisms Underlying Alterations in TJ Structure in Stroke; 6 Non-TJ Pathways Involved in BBB Hyperpermeability After Stroke; 7 Therapeutic Interventions; 8 Conclusions; References; Role of Pericytes in Neurovascular Unit and Stroke
• 1 Neurovascular Unit and Stroke2 Pericytes; 2.1 Regulation of Microcirculatory Blood Flow and BBB by Pericytes; 2.2 Pericytes Are Vulnerable to Ischemic Injury; 3 Changes in Pial and Penetrating Arteries Shortly After Stroke; 4 Incomplete Microcirculatory Reflow After Recanalization; 5 Clinical Evidence for "No-Reflow" After Recanalization Therapies for Stroke; 6 Role of Pericytes in CADASIL; 7 Post-stroke Angioneurogenesis and Pericytes; References; Glial Support of Blood-Brain Barrier Integrity: Molecular Targets for Novel Therapeutic Strategies in Stroke; 1 Introduction
• 2 The Neurovascular Unit2.1 Components of the Neurovascular Unit; 2.1.1 Endothelial Cells and the Blood-Brain Barrier; 2.2 Molecular Characteristics of the BBB; 2.2.1 Tight Junction Protein Complexes; 2.2.2 Adherens Junctions; 2.3 Transporters; 2.4 Astrocytes; 2.5 Microglia; 2.6 Pericytes; 2.7 Neurons; 2.8 Extracellular Matrix; 3 Ischemic Stroke; 3.1 Overview of Ischemic Stroke; 3.2 The Neurovascular Unit in Ischemic Stroke; 3.2.1 Disruption of the Blood-Brain Barrier; 3.3 Ischemic Stroke and Glial Support of the BBB; 3.4 Targeting the Neurovascular Unit in Ischemic Stroke
• 3.4.1 Targeting the Tight Junction3.5 Targeting Endogenous BBB Transporters; 3.6 Targeting Glial Support of the BBB; 4 Conclusion; References; Barrier Mechanisms in Neonatal Stroke; 1 Introduction; 2 Development of the BBB and Other Brain Barriers; 3 Blood-Brain Barrier and Adult Stroke; 4 Maturation-Dependent Susceptibility of the BBB to Inflammation; 5 Models of Neonatal Focal Stroke and Hypoxia-Ischemia; 6 BBB Integrity After Neonatal Focal Stroke and Hypoxia-Ischemia; 7 Leukocyte and BBB Integrity After Neonatal Stroke; 8 BBB Integrity, Angiogenesis and Brain Repair After Neonatal Stroke
• 9 Conclusions and Future DirectionsReferences; Angiogenesis: A Realistic Therapy for Ischemic Stroke; 1 Introduction; 2 Overview of Angiogenesis; 3 Angiogenesis After Ischemic Stroke; 4 Regulation of Angiogenesis After Ischemic Stroke; 5 Functional Roles of Angiogenesis in Stroke Long-Term Remodeling and Functional Recovery; 6 Therapeutic Angiogenesis in Ischemic Stroke; References; Part II: Glial Cells in Stroke; Astrocytes as a Target for Ischemic Stroke; 1 A Brief Overview of Astrocytes; 2 Astrocytes in Ischemic Stroke; 2.1 Astrocyte and Glutamate Uptake in Ischemic Stroke

Control code

SPR956730940

Dimensions

unknown

Extent

1 online resource (xiii, 408 pages)

File format

unknown

Form of item

online

Isbn

9783319323374

Level of compression

unknown

Media category

computer

Media MARC source

rdamedia

Media type code

• c

Other physical details

illustrations

Quality assurance targets

not applicable

Record ID

b4041615

Reformatting quality

unknown

Sound

unknown sound

Specific material designation

remote