Coverart for item
The Resource Squamous cell carcinoma : molecular therapeutic targets, Saman Warnakulasuriya, Zakir Khan, editors

Squamous cell carcinoma : molecular therapeutic targets, Saman Warnakulasuriya, Zakir Khan, editors

Label
Squamous cell carcinoma : molecular therapeutic targets
Title
Squamous cell carcinoma
Title remainder
molecular therapeutic targets
Statement of responsibility
Saman Warnakulasuriya, Zakir Khan, editors
Contributor
Editor
Subject
Language
eng
Summary
This edited volume is about novel targeted therapies for the treatment of advanced neoplasms of the head and neck (HNSCC) with particular reference to oral squamous cell carcinomas and covers specific fields of cancer genetics and genomics for personalized medicine. The landmark studies from the HNSCC Cancer Genome Anatomy (TCGA) and the cancer Genome Atlas 2015 have revealed the multiplicity and diversity of genetic alterations in HNSCC. This remarkable body of information has elucidated novel druggable targets (eg. EGFR, mTOR, p53, survivin and aberrant microRNA) for therapeutic interventions in head and neck cancer. Readers will discover the importance of the biology and pathology of squamous cell carcinomas, the role of cancer stem cells and other factors that contribute to resistance to curative therapies such as hypoxia. We present an in-depth analysis of the HNSCC oncogenome describing the distinct molecular alterations in squamous cell carcinomas, which participate in specific molecular pathways whose dysregulation may contribute to most HNSCC cases. Final chapters of the book elucidate how these important cancer-driving molecular events and molecular pathways could be targeted to treat head and neck cancers and their therapeutic applications for targeted therapies based on clinical trials reported worldwide. This book is aimed at a broad audience, including scientists, physicians, surgeons, and post graduate students engaged in oncology and provide the readers with an up-to-date, interdisciplinary knowledge and tools to better understand the evolving areas of targeted gene therapy and the key concept of personalized medicine in head and neck cancer
Cataloging source
N$T
Dewey number
616.99/477
Illustrations
illustrations
Index
index present
LC call number
RC280.S5
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorDate
1979-
http://library.link/vocab/relatedWorkOrContributorName
  • Warnakulasuriya, S.
  • Khan, Zakir
http://library.link/vocab/subjectName
Squamous cell carcinoma
Label
Squamous cell carcinoma : molecular therapeutic targets, Saman Warnakulasuriya, Zakir Khan, editors
Instantiates
Publication
Note
Includes index
Antecedent source
unknown
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Dimensions
unknown
Extent
1 online resource
File format
unknown
Form of item
online
Isbn
9789402410839
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
ocn980875054
Label
Squamous cell carcinoma : molecular therapeutic targets, Saman Warnakulasuriya, Zakir Khan, editors
Publication
Note
Includes index
Antecedent source
unknown
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Dimensions
unknown
Extent
1 online resource
File format
unknown
Form of item
online
Isbn
9789402410839
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
ocn980875054

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